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快中子和X射线诱导的红细胞对钠和钾离子通透性损伤的“修复”及其被血影促进的作用

'Repair' of fast-neutron and x-ray-induced damage to the permeabilities of red blood cells to sodium and potassium ions and its promotion by ghosts.

作者信息

Suzuki S

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1978 Dec;34(6):513-22. doi: 10.1080/09553007814551211.

Abstract

Damage to the permeability of red blood cells to Na+ and K+ caused by irradiation with fast neutrons or X-rays was investigated at different post-irradiation incubation temperatures. The extent of Na+ uptake and K+ loss by the cells after either radiation was higher at 4 degrees C than at 37 degrees C, but the extent of 'repair' of the damage caused by fast neutrons was lower than that caused by X-rays. The latter 'repair' was promoted by the addition of ghosts, but the former was not. On the other hand neither 'repair' process was influenced by haemolysates from which ghosts had been removed.

摘要

在不同的辐照后孵育温度下,研究了快中子或X射线辐照对红细胞钠钾通透性的损伤。辐照后,细胞对钠的摄取和钾的流失程度在4℃时高于37℃,但快中子造成的损伤“修复”程度低于X射线造成的损伤。添加红细胞影促进了X射线损伤的“修复”,但快中子损伤的“修复”未受促进。另一方面,两种“修复”过程均不受去除红细胞影的溶血产物的影响。

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