Joyner M, Lee R, Hegde U M
Department of Haematology, Royal Devon, Hospital, Exeter, UK.
J Infect. 1987 Jul;15 Suppl 1:51-4. doi: 10.1016/s0163-4453(87)92480-7.
Fifteen patients comprising ten with chronic idiopathic autoimmune thrombocytopenic purpura, three with acute autoimmune thrombocytopenic purpura, and two with secondary chronic autoimmune thrombocytopenic purpura were treated. All patients received 5-day courses of intravenous immunoglobulin (pH 4.25) at a dose of 400 mg kg body weight daily and five patients received maintenance treatment with double dose single infusions. Responses were seen in 12 patients which were in general of brief duration although one patient had a sustained remission. Five patients were treated with maintenance therapy of 800 mg/kg given at approximately 3-weekly intervals and maintained satisfactory platelet counts.
对15例患者进行了治疗，其中包括10例慢性特发性自身免疫性血小板减少性紫癜患者、3例急性自身免疫性血小板减少性紫癜患者和2例继发性慢性自身免疫性血小板减少性紫癜患者。所有患者均接受为期5天的静脉注射免疫球蛋白（pH 4.25）治疗，剂量为每日400mg/kg体重，5例患者接受双倍剂量单次输注的维持治疗。12例患者出现反应，尽管有1例患者持续缓解，但总体反应持续时间较短。5例患者接受每3周左右一次的800mg/kg维持治疗，血小板计数维持在满意水平。
