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大剂量静脉注射免疫球蛋白治疗输血后紫癜

High-dose intravenous immunoglobulin for post-transfusion purpura.

作者信息

Becker T, Panzer S, Maas D, Kiefel V, Sprenger R, Kirschbaum M, Mueller-Eckhardt C

出版信息

Br J Haematol. 1985 Sep;61(1):149-55. doi: 10.1111/j.1365-2141.1985.tb04071.x.

Abstract

Five patients with post-transfusion purpura (four due to Zw(a), one presumably due to HLA antibodies) were treated with intravenous immunoglobulin (IgG) at doses of 0.4 g per kg body weight. IgG therapy was immediately effective as indicated by cessation of bleeding and rise of platelet counts in four out of five cases.

摘要

五名输血后紫癜患者(四名因Zw(a),一名可能因HLA抗体)接受了静脉注射免疫球蛋白(IgG)治疗,剂量为每公斤体重0.4克。五例中有四例出血停止且血小板计数上升,表明IgG治疗立即起效。

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