Then Eric O, Gayam Vijay, Are Vijay S, Sunkara Tagore, Gaduputi Vinaya
Internal Medicine, St. Barnabas Hospital Health System, Bronx, USA.
Internal Medicine, Interfaith Medical Center, Brooklyn, USA.
Cureus. 2019 Mar 25;11(3):e4313. doi: 10.7759/cureus.4313.
Herpes simplex virus (HSV) is a rarely reported cause of viral hepatitis. Aggressive in nature, most cases of HSV hepatitis rapidly progress to fulminant hepatic failure. Present day, its pathogenesis is yet to be elucidated, but its complications and associated high mortality rate are clear. Clinically, its symptoms mimic those of other causes of acute hepatic failure thus making the diagnosis of HSV hepatitis a precarious task. Although treatment in the form of acyclovir is readily available, most cases have a poor prognosis due to late initiation of therapy. This makes the early identification of HSV essential in improving outcomes and potentially preventing mortality.
单纯疱疹病毒（HSV）是一种罕见的病毒性肝炎病因。HSV本质上具有侵袭性，大多数HSV肝炎病例会迅速发展为暴发性肝衰竭。目前，其发病机制尚待阐明，但其并发症和高死亡率是明确的。临床上，其症状与其他急性肝衰竭病因的症状相似，因此诊断HSV肝炎是一项艰巨的任务。尽管有阿昔洛韦这种治疗药物，但由于治疗开始较晚，大多数病例预后较差。这使得早期识别HSV对于改善预后和潜在预防死亡至关重要。
