单纯疱疹病毒性肝炎：多机构病例展示以促进该病的早期诊断与管理
Herpes Simplex Virus Hepatitis: A Presentation of Multi-Institutional Cases to Promote Early Diagnosis and Management of the Disease.
作者信息
Natu Ashwinee, Iuppa Guiseppe, Packer Clifford D
机构信息
Department of Internal Medicine, University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH 44106, USA.
Department of Transplant Surgery, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.
出版信息
Case Reports Hepatol. 2017;2017:3180984. doi: 10.1155/2017/3180984. Epub 2017 Aug 1.
OBJECTIVE
To compare three cases of Herpes simplex virus (HSV) hepatitis to increase early diagnosis of the disease. A 23-year-old man with Crohn's disease and oral HSV. HSV hepatitis was diagnosed clinically and he improved with acyclovir. An 18-year-old G1P0 woman with transaminitis. Despite early empiric acyclovir therapy, she died due to fulminant liver failure. . A 65-year-old woman who developed transaminitis after liver transplant. Diagnosis was confirmed by biopsy and she had resolution of acute liver failure with acyclovir.
CONCLUSION
It is imperative that clinicians be aware of patients at high risk for developing HSV hepatitis to increase timely diagnosis and prevent morbidity and fatality.
目的
比较三例单纯疱疹病毒（HSV）肝炎病例，以提高对该疾病的早期诊断。
一名23岁患有克罗恩病和口腔HSV的男性。临床诊断为HSV肝炎，使用阿昔洛韦治疗后病情好转。
一名18岁、孕1产0、患有转氨酶升高的女性。尽管早期经验性使用阿昔洛韦治疗，但她因暴发性肝衰竭死亡。
一名65岁女性在肝移植后出现转氨酶升高。活检确诊，使用阿昔洛韦后急性肝衰竭得到缓解。
结论
临床医生必须意识到发生HSV肝炎的高危患者，以提高及时诊断率，预防发病和死亡。
Zotero 插件