一名儿科患者甲状旁腺癌的病例报告。

Case report of parathyroid carcinoma in a pediatric patient.

作者信息

Zivaljevic Vladan R, Jovanovic Milan D, Djordjevic Maja S, Diklic Aleksandar D, Paunovic Ivan R

机构信息

Center for Endocrine Surgery, Clinical Center of Serbia, Belgrade, Serbia; School of Medicine University of Belgrade, Serbia.

Center for Endocrine Surgery, Clinical Center of Serbia, Belgrade, Serbia.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 Sep;124:120-123. doi: 10.1016/j.ijporl.2019.06.003. Epub 2019 Jun 5.

DOI:10.1016/j.ijporl.2019.06.003

PMID:31185342

Abstract

Parathyroid carcinoma is extremely rare in pediatric population. The authors report a case of 15-year-old girl with extremely elevated serum calcium (4.1 mmol/L) and parathyroid hormone (1170 pg/mL), with palpable neck mass. After en bloc resection, the patient remained normocalcemic within the next 2 years. To the best of our knowledge, this is the fourteenth documented case of parathyroid carcinoma in patients younger than 16 years. Even though parathyroid carcinoma is very uncommon in children with good prognosis, this diagnosis has to be considered when a child has severe hypercalcemia, elevated parathyroid hormone and palpable neck mass.

摘要

甲状旁腺癌在儿童人群中极为罕见。作者报告了一例15岁女孩，其血清钙（4.1 mmol/L）和甲状旁腺激素（1170 pg/mL）极度升高，颈部可触及肿块。整块切除术后，患者在接下来的2年内血钙保持正常。据我们所知，这是第14例记录在案的16岁以下甲状旁腺癌患者。尽管甲状旁腺癌在儿童中非常罕见且预后良好，但当儿童出现严重高钙血症、甲状旁腺激素升高和颈部可触及肿块时，必须考虑这一诊断。