[胃内源性细菌亚硝酸盐形成的动力学。4. 健康人胃中硝酸盐和亚硝酸盐的定位及相互作用]
[Dynamics of endogenous bacterial nitrite formation in the stomach. 4. Localization and reciprocal action of nitrate and nitrite in the healthy human stomach].
作者信息
Mueller R L, Henninger H
机构信息
Institut für Medizinische Hygiene der Universität Erlangen-Nürnberg.
出版信息
Zentralbl Bakteriol Mikrobiol Hyg B Umwelthyg Krankenhaushyg Arbeitshyg Prav Med. 1987 Jul;184(5):386-402.
The nitrate and nitrite concentrations of 42 fasting gastric juice samples of young healthy human volunteers were analysed. It could be shown by separate determination of the concentration in the real secrete and the mucous gel that the amount of nitrate in the gel is about ten times higher than in the real secrete. The former conception, after which nitrate only gets by swallowed saliva into the stomach, has to be completed. It is obvious that the mucigenous glands of the stomach, like the saliva glands, are also able of nitrate enrichment and secretion. These results are very important for the evaluation of nitrate as a precursor of cancerogenic N-nitroso compounds.
对42名年轻健康人类志愿者的空腹胃液样本中的硝酸盐和亚硝酸盐浓度进行了分析。通过分别测定实际分泌液和黏液凝胶中的浓度可以发现，凝胶中的硝酸盐含量比实际分泌液中的高出约10倍。之前认为硝酸盐仅通过吞咽唾液进入胃中的观点必须修正。显然，胃的黏液腺与唾液腺一样，也能够富集和分泌硝酸盐。这些结果对于评估硝酸盐作为致癌性N-亚硝基化合物的前体非常重要。
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