自闭症谱系障碍患者从青春期到老年的焦虑和抑郁。

Anxiety and Depression from Adolescence to Old Age in Autism Spectrum Disorder.

机构信息

Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford Autism Center, Stanford University, Stanford, CA, USA.

Cooperative Research Centre for Living with Autism (Autism CRC), Long Pocket, Brisbane, QLD, Australia.

出版信息

J Autism Dev Disord. 2020 Sep;50(9):3155-3165. doi: 10.1007/s10803-019-04084-z.

DOI:10.1007/s10803-019-04084-z

PMID:31190198

Abstract

This study examined age trends in anxious and depressive symptoms, from older adolescence to old age, and explored the association between anxious and depressive symptoms with gender, ASD severity, and socio-economic factors. Two hundred and fifty-five individuals with ASD (151 males, M = 33.52 years, SD = 14.98) took part. More than one-third of participants reported clinically significant anxiety (38.4%) or depression (38%). A slight trend for an increase in the severity of both anxiety and depression from adolescence to middle adulthood, and then a slight decline in older adulthood was found. Female gender and higher ASD severity predicted more anxiety and depression symptoms. Our findings emphasise the need to provide timely assessment and treatment of anxiety and depression in ASD.

摘要

本研究考察了从青少年晚期到老年期焦虑和抑郁症状的年龄趋势，并探讨了焦虑和抑郁症状与性别、自闭症严重程度和社会经济因素之间的关系。共有 255 名自闭症患者（男性 151 名，M=33.52 岁，SD=14.98）参与了这项研究。超过三分之一的参与者报告有临床显著的焦虑（38.4%）或抑郁（38%）。研究发现，焦虑和抑郁的严重程度从青少年期到中年期略有增加，然后在老年期略有下降。女性性别和更高的自闭症严重程度预示着更多的焦虑和抑郁症状。我们的研究结果强调了在自闭症中及时评估和治疗焦虑和抑郁的必要性。