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血清游离三碘甲状腺原氨酸改良检测法的诊断价值

Diagnostic value of a modified assay of free triiodothyronine in serum.

作者信息

Forshaw K M, van Heyningen C

机构信息

Department of Pathology, Southport General Infirmary, U.K.

出版信息

Clin Chem. 1987 Nov;33(11):2093-4.

PMID:3119256
Abstract

The performance of a modified commercial (Diagnostic Products Corp.) assay for free triiodothyronine in serum was evaluated, and its diagnostic value was compared with two other methods for free triiodothyronine estimation in euthyroid subjects and in patients with thyroid dysfunction. No advantage was demonstrated for the modified assay as an index of thyroid status. In conditions involving thyroxin-binding globulin excess the modified assay produced misleading results more frequently than did the comparison methods.

摘要

对一种改良的商用(诊断产品公司)血清游离三碘甲状腺原氨酸检测方法的性能进行了评估,并将其诊断价值与另外两种用于评估甲状腺功能正常者及甲状腺功能障碍患者血清游离三碘甲状腺原氨酸的方法进行了比较。作为甲状腺状态指标,改良检测方法未显示出优势。在甲状腺素结合球蛋白过量的情况下,改良检测方法比对照方法更频繁地产生误导性结果。

相似文献

1
Diagnostic value of a modified assay of free triiodothyronine in serum.血清游离三碘甲状腺原氨酸改良检测法的诊断价值
Clin Chem. 1987 Nov;33(11):2093-4.
2
Serum free thyroxine in thyroidal and nonthyroidal illnesses: a comparison of measurements by radioimmunoassay, equilibrium dialysis, and free thyroxine index.甲状腺疾病和非甲状腺疾病中的血清游离甲状腺素:放射免疫测定、平衡透析及游离甲状腺素指数测量方法的比较
J Clin Endocrinol Metab. 1980 Jul;51(1):135-43. doi: 10.1210/jcem-51-1-135.
3
Performance characteristics and diagnostic value (vs other tests) of two radioimmunoassay kits for estimating free triiodothyronine in serum.两种用于估算血清中游离三碘甲状腺原氨酸的放射免疫分析试剂盒的性能特征及诊断价值(与其他检测方法对比)
Clin Chem. 1984 Feb;30(2):216-21.
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Free triiodothyronine and free thyroxin in sera of pregnant women and subjects with congenitally increased or decreased thyroxin-binding globulin.孕妇以及先天性甲状腺素结合球蛋白升高或降低者血清中的游离三碘甲状腺原氨酸和游离甲状腺素
Clin Chem. 1983 Aug;29(8):1527-30.
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Radioimmunoassay of thyroxine-binding globulin: evaluation of a kit and diagnostic application.甲状腺素结合球蛋白的放射免疫测定:试剂盒评估及诊断应用
Ann Clin Biochem. 1980 Sep;17(5):241-6. doi: 10.1177/000456328001700505.
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Chemically blocked analog assays for free thyronines. II. Use of equilibrium dialysis to optimize the displacement by chemical blockers of T4 analog and T3 analog from albumin while avoiding displacement of T4 and T3 from thyroxin-binding globulin.游离甲状腺素的化学阻断类似物分析。II. 使用平衡透析优化化学阻断剂对白蛋白结合的T4类似物和T3类似物的置换,同时避免甲状腺素结合球蛋白上的T4和T3被置换。
Clin Chem. 1988 Jan;34(1):17-23.
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Adapting the total triiodothyronine [T3] radioimmunoassay kit to measure serum free T3.
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Evaluation of a new strategy for detection of thyroid dysfunction in the routine laboratory.常规实验室中甲状腺功能障碍检测新策略的评估
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Estimation of free thyroid hormone concentrations in the clinical laboratory.
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J Clin Endocrinol Metab. 1982 Feb;54(2):300-6. doi: 10.1210/jcem-54-2-300.

引用本文的文献

1
Thyroid function evaluation by different commercially available free thyroid hormone measurement kits in term pregnant women and their newborns.使用不同市售游离甲状腺激素检测试剂盒对足月孕妇及其新生儿进行甲状腺功能评估。
J Endocrinol Invest. 1991 Jan;14(1):1-9. doi: 10.1007/BF03350244.