……中的外排基因
efflux gene in .
作者信息
Xu C, Bilya S R, Xu W
机构信息
Department of Pediatrics, Shengjing Hospital of China Medical University, Liaoning, China.
出版信息
New Microbes New Infect. 2019 Apr 10;30:100549. doi: 10.1016/j.nmni.2019.100549. eCollection 2019 Jul.
The antimicrobial resistance to is significantly high and continues to grow; it has become a global health issue, particularly in regards to carbapenem resistance The expression of efflux pumps is one of the major mechanisms of antibiotic resistance in by, most prevalently, of the resistance/nodulation/division family. The detection rate of was the highest in clinical isolates compared to others (), although it varied among other strains. In this minireview, we explain the efflux gene in causing antibiotic resistance and compare with other efflux genes in order to discern the function of in resistance, which may help in the discovery of new antibacterial agents.
对……的抗菌耐药性非常高且持续增长；它已成为一个全球健康问题，尤其是在碳青霉烯耐药性方面。外排泵的表达是……中抗生素耐药的主要机制之一，最常见的是耐药/结瘤/分裂家族的……。与其他菌株相比，……在临床分离株中的检出率最高（……），尽管在其他菌株中有所不同。在这篇综述中，我们解释了……中导致抗生素耐药的外排基因，并将其与其他外排基因进行比较，以辨别……在……耐药中的作用，这可能有助于发现新的抗菌剂。
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