Gómez-Cerón Stephania, Galindo-Betancur David, Ramírez-Malule Howard
Universidad del Valle, Escuela de Ingeniería Química, A.A. 25360 Cali, Colombia.
Data Brief. 2019 May 15;24:103992. doi: 10.1016/j.dib.2019.103992. eCollection 2019 Jun.
() is a Gram-positive bacterium which produced clavulanic acid (CA) and cephamycin C (CephC). In this data article, a curated genome scale metabolic model of is presented. A total of eighteen objective functions were evaluated for a better representation of CA and CephC production by . The different objective functions were evaluated varying the weighting factors of CA and CephC between 0, 1 y 2, whereas for the case of biomass the weight factor was varied between 1 and 2. A robustness analysis, by mean of flux balance analysis, showed five different metabolic phenotypes of as a function of oxygen uptake: (I) and (II) biomass production, (III) biomass and CephC production, (IV) simultaneous production of biomass, CA and CephC and (V) production of biomass and CA. Data of shadow prices and reduced cost are also presented.
（）是一种产生克拉维酸（CA）和头霉素C（CephC）的革兰氏阳性细菌。在本数据文章中，展示了（）的一个经过整理的基因组规模代谢模型。为了更好地体现（）产生CA和CephC的情况，共评估了18个目标函数。通过改变CA和CephC的加权因子在0、1和2之间，对不同的目标函数进行了评估，而对于生物量的情况，权重因子在1和2之间变化。通过通量平衡分析进行的稳健性分析表明，（）作为氧气摄取量的函数有五种不同的代谢表型：（I）和（II）生物量产生，（III）生物量和CephC产生，（IV）生物量、CA和CephC同时产生，以及（V）生物量和CA产生。还给出了影子价格和缩减成本的数据。
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