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孤立的根癌土壤杆菌所致隐形眼镜相关感染性角膜炎病例:一种现正成为人类病原体的植物微生物。

Case of isolated Rhizobium radiobacter contact lens-related infectious keratitis: A plant microbe now emerging as a human pathogen.

作者信息

Fenner Beau J, Kumar Ashish, Tan Nicholas Y Q, Ang Marcus

机构信息

Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore.

Singapore Eye Research Institute, 20 College Road Discovery Tower Level 6, The Academia, Singapore.

出版信息

Am J Ophthalmol Case Rep. 2019 May 30;15:100476. doi: 10.1016/j.ajoc.2019.100476. eCollection 2019 Sep.

Abstract

PURPOSE

To report a case of contact lens-related infectious keratitis caused by the Gram-negative plant pathogen .

OBSERVATIONS

A 26-year old lady with history of contact lens use presented with three weeks history of right eye redness and pain, with the left eye also being involved in the past week. Slit lamp examination of the right eye demonstrated multiple faint subepithelial and stromal infiltrates with no overlying epithelial defect, and no anterior chamber activity. Anterior segment optical coherence tomography demonstrated multiple hyper-reflective foci scattered at various depths of the corneal stroma. Corneal scrapings grew , and culture-directed antibiotic therapy with topical gentamicin and levofloxacin resulted in slow clinical improvement of the keratitis without visual sequelae.

CONCLUSIONS AND IMPORTANCE

We have described the clinical features, microbial susceptibilities, and response to treatment in a case of infectious keratitis.R. radiobacter has recently emerged as a source for several ocular and systemic infections and was identified in a series of polymicrobial keratitis cases. Our case report of monomicrobial keratitis adds to the sparse literature on this uncommon but potentially sight-threatening infection.

摘要

目的

报告一例由革兰氏阴性植物病原体引起的与隐形眼镜相关的感染性角膜炎病例。

观察结果

一名有隐形眼镜使用史的26岁女性,右眼发红、疼痛三周,左眼在过去一周也受到影响。右眼裂隙灯检查显示多处轻微的上皮下和基质浸润,无上皮缺损,无前房炎症。眼前节光学相干断层扫描显示多个高反射灶散在角膜基质的不同深度。角膜刮片培养出……,局部使用庆大霉素和左氧氟沙星进行培养指导的抗生素治疗使角膜炎临床症状缓慢改善,未遗留视力后遗症。

结论与重要性

我们描述了一例……感染性角膜炎的临床特征、微生物敏感性及治疗反应。放射根瘤菌最近已成为多种眼部和全身感染的来源,并在一系列混合性角膜炎病例中被发现。我们关于单一微生物……角膜炎的病例报告补充了关于这种罕见但可能威胁视力的感染的稀少文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbf2/6545415/c14a4cb3ba04/gr1.jpg

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