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放射根瘤菌:细菌性角膜炎的一种新发现病因

Rhizobium radiobacter: A Recently Recognized Cause of Bacterial Keratitis.

作者信息

Barker Nigel H, Thompson Jordan M, Mullen Martin G, Weekes Melissa A, Nguyen Linda N, Haynes Crystal K M, Miller Darlene

机构信息

*Department of Ophthalmology, Queen Elizabeth Hospital, Bridgetown, Barbados;†Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL;‡Department of Ophthalmology, Loyola University Chicago, Maywood, IL;§University of Miami Miller School of Medicine, Miami, FL; and‖Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL.

出版信息

Cornea. 2016 May;35(5):679-82. doi: 10.1097/ICO.0000000000000780.

Abstract

PURPOSE

To present the first reported cases of keratitis caused by Rhizobium radiobacter.

METHODS

A retrospective review of an observational case series from 2 institutions.

RESULTS

There were 4 cases of microbiologically proven R. radiobacter. Three of these patients were contact lens wearers. The patient in case 4 defaulted from follow-up after receipt of the culture result. Keratitis in the other cases resolved with variable clinical courses once culture-directed therapy was instituted.

CONCLUSIONS

R. radiobacter is a member of the genus Rhizobium. It is a gram-negative bacillus and was previously identified as an opportunistic pathogen in nonophthalmic infections and in a few cases of endophthalmitis. To our knowledge, we have described the clinical presentation, management, and treatment outcomes of the first reported cases of keratitis caused by R. radiobacter.

摘要

目的

报告首例由放射根瘤菌引起的角膜炎病例。

方法

对来自2家机构的观察性病例系列进行回顾性研究。

结果

有4例经微生物学证实为放射根瘤菌感染。其中3例患者为隐形眼镜佩戴者。病例4的患者在收到培养结果后失访。一旦开始采用针对性培养的治疗方法,其他病例的角膜炎均以不同的临床病程得到缓解。

结论

放射根瘤菌是根瘤菌属的成员。它是一种革兰氏阴性杆菌,以前被确定为非眼科感染和少数眼内炎病例中的机会致病菌。据我们所知,我们描述了首例由放射根瘤菌引起的角膜炎病例的临床表现、管理和治疗结果。

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