BHumNut, BPharm (Hons), GradCertPharmPrac, Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Vic. jacquelina.
BPharm (Hons), PhD, Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Vic; NHMRC Cognitive Decline Partnership Centre, Hornsby Ku-ring-gai Hospital, Hornsby, NSW; NHMRC Centre for Research Excellence in Frailty and Healthy Ageing, Adelaide, SA; School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic; Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA
Aust J Gen Pract. 2018 Oct;47(10):675-681. doi: 10.31128/AJGP-05-18-4582.
Medication management of type 2 diabetes mellitus (T2DM) in residential aged care facilities (RACFs) requires consideration of the residents’ goals of care and susceptibility to adverse drug events (ADEs).
The aim of this article is to review best practice medication management for residents diagnosed with T2DM.
Management of T2DM in RACFs is often focused on maintaining residents’ quality of life rather than intensive glycaemic management to reduce chronic complications, because the risks of intensive glycaemic management typically outweigh the potential benefits. Australian RACF guidelines recommend individualised glycated haemoglobin targets of 7–8.5% (53–69 mmol/mol). Strategies to reduce the risk of preventable ADEs may include education for residents, carers and staff; assessment of hypoglycaemic risk and renal function; medication review and regimen simplification; de-intensification of glucose-lowering medications; and appropriate end-of-life medication management. Use of a resident-centred multidisciplinary approach and resources tailored to the RACF setting will support residents to achieve best possible health outcomes and quality of life.
在养老院(RACF)中对 2 型糖尿病(T2DM)患者进行药物管理需要考虑居民的护理目标和对药物不良事件(ADE)的易感性。
本文旨在回顾诊断为 T2DM 的居民的最佳药物管理实践。
RACF 中 T2DM 的管理通常侧重于维持居民的生活质量,而不是强化血糖管理以减少慢性并发症,因为强化血糖管理的风险通常超过潜在益处。澳大利亚 RACF 指南建议个体化糖化血红蛋白目标为 7-8.5%(53-69mmol/mol)。降低可预防 ADE 风险的策略可能包括对居民、护理人员和工作人员进行教育;评估低血糖风险和肾功能;药物审查和方案简化;降低降糖药物的强度;以及适当的临终药物管理。使用以居民为中心的多学科方法和针对 RACF 环境的资源将支持居民实现最佳健康结果和生活质量。