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[后路短节段固定联合骨水泥强化治疗合并椎管狭窄的 Kümmell 病的疗效]

[Effectiveness of posterior short-segmental fixation with bone cement augmentation for stage Kümmell's disease with spinal canal stenosis].

作者信息

Chen Hao, Yang Junsong, Hao Dingjun

机构信息

Xi'an Medical University, Xi'an Shaanxi, 710021, P.R.China;Department of Spine Surgery, Honghui Hospital Affiliated to Medical School of Xi'an Jiaotong University, Xi'an Shaanxi, 710054, P.R.China.

Department of Spine Surgery, Honghui Hospital Affiliated to Medical School of Xi'an Jiaotong University, Xi'an Shaanxi, 710054, P.R.China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2019 Jun 15;33(6):707-711. doi: 10.7507/1002-1892.201902001.

Abstract

OBJECTIVE

To investigate the effectiveness of posterior short-segmental fixation with bone cement augmentation in treatment of stage Ⅲ Kümmell's disease with spinal canal stenosis.

METHODS

Between June 2012 and January 2017, 36 patients with stage Ⅲ Kümmell's disease and spinal canal stenosis were treated by posterior short-segmental fixation and bone cement augmentation. There were 12 males and 24 females, aged 55-83 years (mean, 73.5 years). The disease duration ranged from 2 to 8 months, with an average of 4.6 months. Preoperative bone mineral density examination showed that all patients had different degrees of osteoporosis in the spines. The lesion segments included T in 4 cases, T in 7 cases, T in 8 cases, L in 9 cases, and L in 8 cases. The preoperative neural function was classified as grade B in 4 cases, grade C in 12 cases, grade D in 13 cases, and grade E in 7 cases according to Frankle classification. The operation time, intraoperative blood loss, and the volume of injected bone cement, and hospital stay were recorded. The visual analogue scale (VAS) score, Oswestry Disability Index (ODI), kyphotic Cobb angle, and the height of anterior edge of injured vertebra were recorded before operation, at 1 week after operation, and at last follow-up; and the leakage of bone cement was observed.

RESULTS

All operations were completed successfully. The operation time was 90-145 minutes (mean, 110.6 minutes); the intraoperative blood loss was 198-302 mL (mean, 242.5 mL); the volume of injected bone cement was 8.3-10.5 mL (mean, 9.2 mL); the hospital stays were 7-12 days (mean, 8.3 days). All patients were followed up 12-26 months (mean, 24.5 months). At 1 week after operation, the neural function was classified as grade B in 2 cases, grade C in 8 cases, grade D in 12 cases, and grade E in 14 cases, which was significantly improved when compared with that before operation ( =2.000, =0.047). The VAS score, ODI, the height of anterior edge of injured vertebra, and Cobb angle were significantly improved at 1 week and last follow-up when compared with preoperative values ( <0.05); but there was no significant difference between 1 week and last follow-up ( >0.05). Two cases had asymptomatic cement leakage to the intervertebral disc at 1 week after operation; and 1 case had adjacent vertebral fracture at 8 months after operation. No complication such as loosening or breaking of internal fixator occurred during the follow-up.

CONCLUSION

Posterior short-segmental fixation with bone cement augmentation is a safe and effective surgical scheme for stage Ⅲ Kümmell's disease combined with spinal canal stenosis, which can avoid the aggravation of nerve injury and complications related to staying in bed.

摘要

目的

探讨后路短节段固定联合骨水泥强化治疗Ⅲ期Kümmell病合并椎管狭窄的疗效。

方法

2012年6月至2017年1月,对36例Ⅲ期Kümmell病合并椎管狭窄患者采用后路短节段固定联合骨水泥强化治疗。其中男性12例,女性24例,年龄55 - 83岁(平均73.5岁)。病程2 - 8个月,平均4.6个月。术前骨密度检查显示所有患者脊柱均有不同程度骨质疏松。病变节段包括胸4 4例,胸5 7例,胸6 8例,腰1 9例,腰2 8例。术前神经功能按Frankle分级:B级4例,C级12例,D级13例,E级7例。记录手术时间、术中出血量、骨水泥注入量及住院时间。记录术前、术后1周及末次随访时的视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、后凸Cobb角及伤椎前缘高度;观察骨水泥渗漏情况。

结果

所有手术均顺利完成。手术时间90 - 145分钟(平均110.6分钟);术中出血量198 - 302 mL(平均242.5 mL);骨水泥注入量8.3 - 10.5 mL(平均9.2 mL);住院时间7 - 12天(平均8.3天)。所有患者随访12 - 26个月(平均24.5个月)。术后1周神经功能:B级2例,C级8例,D级12例,E级14例,与术前相比有明显改善( =2.000, =0.047)。术后1周及末次随访时VAS评分、ODI、伤椎前缘高度及Cobb角与术前相比均有明显改善( <0.05);但术后1周与末次随访之间差异无统计学意义( >0.05)。术后1周2例骨水泥无症状渗漏至椎间盘;术后8个月1例发生邻近椎体骨折。随访期间未发生内固定松动或断裂等并发症。

结论

后路短节段固定联合骨水泥强化是治疗Ⅲ期Kümmell病合并椎管狭窄的一种安全有效的手术方案,可避免神经损伤加重及卧床相关并发症发生。

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引用本文的文献

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[Comparison of short-segment and long-segment bone cement-augmented fixation combined with vertebroplasty in treatment of stage Kümmell disease].
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本文引用的文献

1
[Effectiveness comparison between two operations in treatment of unstable type Kümmell's disease].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017 Feb 15;31(2):185-190. doi: 10.7507/1002-1892.201608096.
2
Failed percutaneous kyphoplasty in treatment of stage 3 Kummell disease: A case report and literature review.
Medicine (Baltimore). 2017 Nov;96(47):e8895. doi: 10.1097/MD.0000000000008895.
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