Zhang Yun, Gao Guan, Wang Lei, Li Zhichao, Dong Jianwen, Xue Jingcai
College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan Shandong, 250001, P.R.China.
Department of Orthopedics, Weihaiwei People's Hospital, Weihai Shandong, 264200, P.R.China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2021 Apr 15;35(4):464-470. doi: 10.7507/1002-1892.202010042.
To report an improved classification system of Kümmell's disease and its clinical application.
Based on CT and MRI, an improved classification system of Kümmell's disease was proposed in terms of the integrity of sagittal endplate, the integrity of posterior wall of vertebral body, and the degree of vertebral compression. Between January 2011 and March 2018, the improved classification system was used to evaluate and guide the treatment of 78 patients with Kümmell's disease. There were 13 males and 65 females. The mean age was 69.1 years (range, 54-85 years). The mean disease duration was 4.0 months (range, 1-8 months). The mean T value of bone mineral density was -3.66 (range, -3.86- -3.34).The fractures located at thoracic vertebrae in 47 cases and lumbar vertebrae in 31 cases. According to the modified classification system of Kümmell's disease, there were 11 cases of type A1, 13 cases of type A2, 2 cases of type A3, 10 cases of type B1, 18 cases of type B2, 4 cases of type B3, 4 cases of type C1, 5 cases of type C2, and 11 cases of type C3. According to the classification results, the patients of types A and B were treated with percutaneous kyphoplasty (PKP), while the patients of type C were treated with PKP or intra- vertebral fixation according to the degree of vertebral reduction. Visual analogue scale (VAS) score and Oswestry Disability Index (ODI) were used to evaluate clinical efficacy. The heights of the anterior, middle, and posterior edges of the vertebrae and the Cobb angle were measured to evaluate the reduction of the injured vertebrae and the improvement of kyphosis deformity. The complications were recorded.
The statistical analysis showed that the improved classification system has good consistency. All patients were followed up 12-36 months (mean, 24.3 months). The heights of anterior, middle, and posterior edges of the vertebrae, Cobb angle, VAS score, and ODI of all types of patients at last follow-up showed significant differences when compared with those before operation ( <0.05). After operation, 4 patients of type A2 had different degree of vertebral height loss; 2 patients of type B2, 3 patients of type C1, and 2 patients of type C2 developed asymptomatic bone cement leakage during PKP; 2 patients of type B3 and 3 patients of type C2 underwent percutaneous internal fixation and vertebral augmentation due to bone cement loosening.
The modified classification system of Kümmell's disease can be used to guide treatment of Kümmell's disease, but the number of clinical application cases is limited, and further application and observation are needed.
报告一种改良的Kümmell病分类系统及其临床应用。
基于CT和MRI,根据矢状位终板完整性、椎体后壁完整性及椎体压缩程度,提出改良的Kümmell病分类系统。2011年1月至2018年3月,采用该改良分类系统对78例Kümmell病患者进行评估并指导治疗。其中男性13例,女性65例。平均年龄69.1岁(范围54 - 85岁)。平均病程4.0个月(范围1 - 8个月)。骨密度平均T值为 - 3.66(范围 - 3.86至 - 3.34)。骨折位于胸椎47例,腰椎31例。根据改良的Kümmell病分类系统,A1型11例,A2型13例,A3型2例,B1型10例,B2型18例,B3型4例,C1型4例,C2型5例,C3型11例。根据分类结果,A、B型患者采用经皮椎体后凸成形术(PKP)治疗,C型患者根据椎体复位程度采用PKP或椎体内固定治疗。采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估临床疗效。测量椎体前缘、中部和后缘高度及Cobb角,评估伤椎复位及后凸畸形改善情况。记录并发症。
统计学分析显示改良分类系统具有良好一致性。所有患者随访12 - 36个月(平均24.3个月)。末次随访时各类型患者椎体前缘、中部和后缘高度、Cobb角、VAS评分及ODI与术前相比差异均有统计学意义(<0.05)。术后,A2型4例患者出现不同程度椎体高度丢失;B2型2例、C1型3例、C2型2例患者在PKP术中出现无症状骨水泥渗漏;B3型2例、C2型3例患者因骨水泥松动行 percutaneous internal fixation and vertebral augmentation(经皮内固定及椎体强化术)。
改良Kümmell病分类系统可用于指导Kümmell病治疗,但临床应用病例数有限,需进一步应用及观察。 (注:原文中“percutaneous internal fixation and vertebral augmentation”直译为“经皮内固定及椎体强化术”,可能是一种特定的医学术语,若有更准确的中文表述,可根据实际情况调整。)