Circuits & Systems Group, Electrical Engineering, Mathematics and Computer Science Faculty, Delft University of Technology, The Netherlands.
Department of Radiology, C.J. Gorter Center for High-Field MRI, Leiden University Medical Center, The Netherlands.
Magn Reson Med. 2019 Nov;82(5):1822-1831. doi: 10.1002/mrm.27849. Epub 2019 Jun 14.
One of the main concerns in fetal MRI is the radiofrequency power that is absorbed both by the mother and the fetus. Passive shimming using high permittivity materials in the form of "dielectric pads" has previously been shown to increase the efficiency and homogeneity in different applications, while reducing the specific absorption rate (SAR). In this work, we study the effect of optimized dielectric pads for 3 pregnant models.
Pregnant models in the 3rd, 7th, and 9th months of gestation were used for simulations in a birdcage coil at 3T. Dielectric pads were optimized regions of interest (ROI) using previously developed methods for efficiency and homogeneity and were designed for 2 ROIs: the entire fetus and the brain of the fetus. The SAR was evaluated in terms of the whole-body SAR, average SAR in the fetus and amniotic fluid, and maximum 10 g-averaged SAR in the mother, fetus, and amniotic fluid.
The optimized dielectric pads increased the transmit efficiency up to 55% and increased the homogeneity in almost every tested configuration. The -normalized whole-body SAR was reduced by more than 31% for all body models. The -normalized local SAR was reduced in most scenarios by up to 62%.
Simulations have shown that optimized high permittivity pads can reduce SAR in pregnant subjects at the 3rd, 7th, and 9th month of gestation, while improving the transmit field homogeneity in the fetus. However, significantly more work is required to demonstrate that fetal imaging is safe under standard operating conditions.
胎儿 MRI 中的主要关注点之一是母体和胎儿吸收的射频功率。以前已经证明,使用高介电常数材料形式的“介电垫”进行被动调谐可以提高不同应用中的效率和均匀性,同时降低比吸收率(SAR)。在这项工作中,我们研究了针对 3 个孕妇模型的优化介电垫的效果。
在 3T 的鸟笼线圈中对处于第 3、7 和 9 个月妊娠的孕妇模型进行了模拟。使用先前开发的效率和均匀性优化方法对介电垫进行了优化,设计了 2 个感兴趣区域(ROI):整个胎儿和胎儿的大脑。SAR 是根据全身 SAR、胎儿和羊水的平均 SAR 以及母亲、胎儿和羊水的最大 10g 平均 SAR 来评估的。
优化的介电垫将发射效率提高了 55%,并几乎在每个测试配置中都提高了均匀性。对于所有体型模型,归一化后的全身 SAR 降低了 31%以上。在大多数情况下,归一化后的局部 SAR 降低了 62%。
模拟表明,优化的高介电常数垫可以降低妊娠第 3、7 和 9 个月孕妇的 SAR,同时提高胎儿的发射场均匀性。然而,需要做更多的工作来证明在标准操作条件下胎儿成像的安全性。