Integral MR-EPT With the Calculation of Coil Current Distributions.

Many integral equation (IE)-based magnetic resonance electrical property tomography (MR-EPT) methods use unloaded incident radio-frequency (RF) fields from simulations that may not fully reflect the real situation and thus lead to reconstruction errors. To improve the accuracy of IE-based MR-EPT methods, a novel approach that enables the calculation of loaded coil current distributions and avoids the explicit use of incident RF fields is presented in this paper. In the proposed method, a hybrid source composed of the current source from the coil and the contrast source from the subject are introduced in the integral equations. Because the loaded coil current distributions can be extracted from the reconstructed hybrid source, the simulated incident RF fields are eliminated from the problem formulations. To improve the convergence performance, a modified conjugate gradient (CG) scheme was used where the gradients of the current source and contrast source were balanced through using different weighting parameters. The proposed method was verified through full-wave simulations at 9.4 and 7 T involving a heterogeneous ball and an anatomical head phantom. The numerical results indicated that by using the proposed method, an accurate coil current distributions and EPs profiles can be reconstructed and the desirable robustness against noise can also be achieved.