Zhang Bo, Fan Zhengning, Guo Zhiqiang, Xi Chanjuan
MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry , Tsinghua University , Beijing 100084 , China.
Scientific Instrument Center , Shanxi University , Taiyuan 030006 , China.
J Org Chem. 2019 Jul 5;84(13):8661-8667. doi: 10.1021/acs.joc.9b01180. Epub 2019 Jun 14.
We report a tandem reaction to realize reduction of carbon dioxide with thiophenols to generate aryl methyl sulfides under the NaBH/I system with 18-crown-6 as the solvent. Thiophenols bearing electron-donating and electron-withdrawing groups are feasible in this reaction. Controlled experiment results indicate that 18-crown-6 plays a critical role in six-electron reduction of carbon dioxide.
我们报道了一种串联反应，该反应可在以18-冠-6为溶剂的NaBH/I体系下，实现二氧化碳与苯硫酚反应还原生成芳基甲基硫醚。带有供电子基团和吸电子基团的苯硫酚在该反应中均可行。对照实验结果表明，18-冠-6在二氧化碳的六电子还原过程中起关键作用。
