Azami Ahad, Anari Hasan, Iranparvar Manouchehr, Azizi Amin, Habibzadeh Afshin
Department of Internal Medicine, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil, Iran.
Department of Radiology, Ardabil University of Medical Sciences, Ardabil, Iran.
Clin Med Insights Arthritis Musculoskelet Disord. 2019 May 14;12:1179544119849017. doi: 10.1177/1179544119849017. eCollection 2019.
In this study, we aim to evaluate the bone mineral density (BMD) results of 2 standard sites with 3 sites including wrist in diagnosing osteoporosis.
We evaluated the BMD results of 1272 individuals referred for suspected osteoporosis between 2012 and 2015. Those individuals were included with BMD at lumbar spine, femur neck, and wrist. Bone mineral density was measured using a dual-energy X-ray absorptiometry (DXA) device. Bone mineral density and score were measured for all 3 sites.
There was significant correlation between wrist score with hip score ( = 0.606, < .001) and lumbar score ( = 0.527, < .001). With BMD of 2 sites, patients had osteopenia in 46.3% and osteoporosis in 23.7%, while by adding wrist T-BMD, subjects had osteopenia in 46.6% and osteoporosis in 33%. Between BMD at 2 sites and 3 sites, there was concordance in 81.9%, minor discordance in 17.6%, and major discordance in 0.5%.
We observed discordance between BMD measurements of 2 sites and 3 sites, with latter detecting more cases with osteoporosis. In fact, measurement of scores of wrist along with lumbar and femur neck improves the diagnosis.
在本研究中,我们旨在评估包括腕部在内的3个部位的2个标准部位的骨密度(BMD)结果在诊断骨质疏松症中的作用。
我们评估了2012年至2015年间因疑似骨质疏松症而转诊的1272名个体的BMD结果。这些个体包括腰椎、股骨颈和腕部的BMD。使用双能X线吸收法(DXA)设备测量骨密度。对所有3个部位测量骨密度和T值。
腕部T值与髋部T值(r = 0.606,P <.001)和腰椎T值(r = 0.527,P <.001)之间存在显著相关性。对于2个部位的BMD,患者骨质减少的比例为46.3%,骨质疏松的比例为23.7%,而加入腕部T-BMD后,受试者骨质减少的比例为46.6%,骨质疏松的比例为33%。在2个部位和3个部位的BMD之间,一致性为81.9%,轻微不一致为17.6%,严重不一致为0.5%。
我们观察到2个部位和3个部位的BMD测量结果之间存在不一致,3个部位的测量能检测出更多骨质疏松症病例。事实上,测量腕部以及腰椎和股骨颈的T值可改善诊断。