Olibamoyo Olushola, Adewuya Abiodun, Ola Bolanle, Coker Olurotimi, Atilola Olayinka
Department of Psychiatry, Lagos State University Teaching Hospital, Lagos, Nigeria.
Department of Behavioural Medicine, Lagos State University College of Medicine, Lagos, Nigeria.
S Afr J Psychiatr. 2019 May 20;25:1252. doi: 10.4102/sajpsychiatry.v25i0.1252. eCollection 2019.
There is mixed evidence for the hypothesis that the risk of depression after stroke is influenced by the location of lesions in the hemispheres, demographic and clinical factors, and disability of stroke survivors.
The current study determined the prevalence of depression and its socio-demographic and clinico-pathological correlates among stroke survivors in a tertiary hospital in Lagos, Nigeria.
The cross-sectional study was carried out among 112 adult patients with a clinical history of stroke confirmed by neuroimaging. Depression was diagnosed using Mini International Neuropsychiatric Interview. The socio-demographic profile was obtained, and cognitive impairment was assessed using the Mini-Mental State Examination. Stroke severity was assessed retrospectively using the National Institute of Health Stroke Scale and current disability was measured using the Modified Rankin Scale.
There were 48 (42.9%) stroke survivors with a clinical diagnosis of depression. Using binary logistic regression, the independent determinants of depression were younger age, unemployment, perceived poor social support, increasing number of previous admissions because of stroke, cognitive impairment, severity of stroke and current disability status. However, there was no significant association between depression and lesion location.
Depression is a common associate of stroke, and there is a need for sustained focus on young stroke survivors with severe stroke, especially those who do not have social support and have low socio-economic status, who may have a higher risk of developing depression following stroke.
关于中风后抑郁风险受半球病变位置、人口统计学和临床因素以及中风幸存者残疾情况影响这一假说,证据不一。
本研究确定了尼日利亚拉各斯一家三级医院中风幸存者中抑郁症的患病率及其社会人口统计学和临床病理相关因素。
对112名有神经影像学确诊中风临床病史的成年患者进行了横断面研究。使用迷你国际神经精神访谈诊断抑郁症。获取社会人口统计学资料,并使用简易精神状态检查表评估认知障碍。使用美国国立卫生研究院中风量表回顾性评估中风严重程度,使用改良Rankin量表测量当前残疾情况。
有48名(42.9%)中风幸存者临床诊断为抑郁症。使用二元逻辑回归分析,抑郁症的独立决定因素为年龄较小、失业、感知到的社会支持差、因中风既往住院次数增加、认知障碍、中风严重程度和当前残疾状态。然而,抑郁症与病变位置之间无显著关联。
抑郁症是中风的常见伴发症,需要持续关注中风严重的年轻幸存者,尤其是那些没有社会支持且社会经济地位较低的人,他们中风后发生抑郁症的风险可能更高。