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巴赫达尔市公立专科医院医疗转诊诊所随访患者中卒中后抑郁的患病率及相关因素

Prevalence and associated factors of post-stroke depression among patients on follow-up at medical referral clinics of Bahir Dar city public specialized hospitals.

作者信息

Debebe Ermiyas Yemane, Biyadgie Mulugeta, Chekol Hanamariam Abebe, Asmare Lakew, Yigzaw Zeamanuel Anteneh

机构信息

Department of Internal Medicine, Eka Kotebe General Hospital, Addis Ababa, Ethiopia.

Department of Internal Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

出版信息

BMC Neurol. 2024 Dec 4;24(1):470. doi: 10.1186/s12883-024-03974-9.

Abstract

BACKGROUND

Post-stroke depression is among the most common neuropsychiatric complications in stroke survivors. Post-stroke depression is commonly under-recognized and under-treated. This study aimed to assess the prevalence and associated factors of post-stroke depression among patients on follow-up at medical referral clinics of Bahir Dar City public specialized hospitals.

METHOD

An institutional-based prospective cross-sectional study was conducted from September to December 2023 on 394 patients. Public Health Questionnaire-9 was used to diagnose depression. Data was checked for cleanness manually and then exported to SPSS version 25 software for analysis. A systematic randomized sampling method was used to identify study participants. Bivariate and multivariate logistic regression analysis was performed to identify independent predictors of post-stroke depression. A p-value less than 0.05 is considered as significant with a 95% confidence interval.

RESULT

The overall prevalence of post-stroke depression was found to be 42.9%. Employment status (AOR = 0.282, 95% CI: 0.112-0.709 C, P-value = 0.007), depression before stroke (AOR = 3.237, 95% CI: 1.098-9.544, P-value = 0.033), ischemic heart disease (AOR = 4.090, 95% CI: 1.745-9.583, P-value = 0.001) and physical disability (AOR = 4.051 95% CI: 2.239-7.332, P-value = 0.000) were found to be statistically significant independent predictors of post-stroke depression (PSD).

CONCLUSION

The prevalence of post-stroke depression was found to be high relative to other similar studies. Patients with known depression before stroke, ischemic heart disease, and significant physical disability were at a higher risk of developing PSD. Employed patients had less risk of developing PSD. Sufficient and comprehensive evaluation of stroke patients for depression is recommended.

摘要

背景

中风后抑郁是中风幸存者中最常见的神经精神并发症之一。中风后抑郁通常未得到充分认识和治疗。本研究旨在评估在巴赫达尔市公立专科医院医疗转诊诊所接受随访的患者中中风后抑郁的患病率及相关因素。

方法

2023年9月至12月对394例患者进行了一项基于机构的前瞻性横断面研究。采用《公共卫生问卷-9》诊断抑郁。数据先手动检查完整性,然后导出到SPSS 25版软件进行分析。采用系统随机抽样方法确定研究参与者。进行二元和多因素逻辑回归分析以确定中风后抑郁的独立预测因素。p值小于0.05被认为具有统计学意义,置信区间为95%。

结果

发现中风后抑郁的总体患病率为42.9%。就业状况(调整后比值比[AOR]=0.282,95%置信区间[CI]:0.112 - 0.709,P值=0.007)、中风前抑郁(AOR = 3.237,95% CI:1.098 - 9.544,P值=0.033)、缺血性心脏病(AOR = 4.090,95% CI:1.745 - 9.583,P值=0.001)和身体残疾(AOR = 4.051,95% CI:2.239 - 7.332,P值=0.000)被发现是中风后抑郁(PSD)的统计学显著独立预测因素。

结论

与其他类似研究相比,发现中风后抑郁的患病率较高。中风前已知患有抑郁、缺血性心脏病和严重身体残疾的患者发生PSD的风险较高。就业患者发生PSD的风险较低。建议对中风患者进行充分和全面的抑郁评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efff/11616239/9f0ff39bc3f3/12883_2024_3974_Fig1_HTML.jpg

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