硫醇对淋巴细胞（T 型淋巴细胞）功能影响的研究。

Studies on the influence of thiols on lymphocytes (T-type lymphocytes) function.

作者信息

Ryzewski J, Krzystyniak K

出版信息

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):361-5.

Abstract

Changes of the oxidation/reduction potential of the coupled -SH/SS low molecular sulfhydryl system in rat lymphocytes were determined after incubation of cells with D-penicillamine, cysteine and cysteine hydrazide, in concentration of thiols which did not disturb the response of the cells to phytohemagglutinin (PHA). Considerable increase of the -SH content in lymphocytes was observed after treatment of the cells with cysteine and cysteine hydrazide. Our findings suggest that the biological effect of thiols used in optimal concentrations and conditions might be coupled with the disturbance of the -SH/SS oxidation/reduction system in cells.

摘要

在用D-青霉胺、半胱氨酸和半胱氨酸酰肼孵育大鼠淋巴细胞后，测定了-SH/SS偶联的低分子巯基系统氧化/还原电位的变化，所用巯基浓度不会干扰细胞对植物血凝素（PHA）的反应。在用半胱氨酸和半胱氨酸酰肼处理细胞后，观察到淋巴细胞中-SH含量显著增加。我们的研究结果表明，在最佳浓度和条件下使用的巯基的生物学效应可能与细胞中-SH/SS氧化/还原系统的紊乱有关。

相似文献

1

Studies on the influence of thiols on lymphocytes (T-type lymphocytes) function.硫醇对淋巴细胞（T 型淋巴细胞）功能影响的研究。

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):361-5.

2

Studies on the influence of thiols on lymphocytes (T-type lymphocytes) functions.硫醇对淋巴细胞（T 型淋巴细胞）功能影响的研究。

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):367-70.

3

Cysteine-induced changes of low molecular sulfhydryl/disulfide ratio in rat lymphoid cells.

Arch Immunol Ther Exp (Warsz). 1989;37(1-2):37-47.

4

Interaction of 6,6'-dithiodinicotinic acid with rat thymocytes pretreated with thiol compounds.6,6'-二硫代烟酸与经硫醇化合物预处理的大鼠胸腺细胞的相互作用。

Arch Immunol Ther Exp (Warsz). 1976;24(1):109-14.

5

Studies on cyclic AMP-cyclic GMP cooperation and on the influence of acetylcholine, adrenaline and thiols in lymphocyte reactivity.关于环磷酸腺苷 - 环磷酸鸟苷协同作用以及乙酰胆碱、肾上腺素和硫醇对淋巴细胞反应性影响的研究。

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):357-9.

6

Immune oxidative injury induced in mice exposed to normobaric O2: effects of thiol compounds on the splenic cell sulfhydryl content and Con A proliferative response.常压氧暴露诱导小鼠产生的免疫性氧化损伤：硫醇化合物对脾细胞巯基含量及伴刀豆球蛋白A增殖反应的影响

J Immunol. 1985 Sep;135(3):2045-51.

7

Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state.成人T细胞白血病（ATL）衍生因子/人硫氧还蛋白可防止由L-胱氨酸和谷胱甘肽耗竭诱导的淋巴细胞凋亡：硫醇介导的氧化还原调节可能参与了由促氧化状态引起的细胞凋亡。

J Immunol. 1997 Apr 1;158(7):3108-17.

8

Concentrations of low and high molecular weight thiols in wheat dough as affected by different concentrations of ascorbic acid.不同浓度抗坏血酸对小麦面团中低分子量和高分子量硫醇浓度的影响。

J Agric Food Chem. 2003 Aug 13;51(17):4948-53. doi: 10.1021/jf0260601.

9

Growth-associated modifications of low-molecular-weight thiols and protein sulfhydryls in human bronchial fibroblasts.人支气管成纤维细胞中低分子量硫醇和蛋白质巯基的生长相关修饰

J Cell Physiol. 1990 Apr;143(1):165-71. doi: 10.1002/jcp.1041430123.

10

Minor thiols cysteine and cysteinylglycine regulate the competition between glutathione and protein SH groups in human platelets subjected to oxidative stress.微量硫醇半胱氨酸和半胱氨酰甘氨酸可调节遭受氧化应激的人体血小板中谷胱甘肽和蛋白质巯基之间的竞争。

Arch Biochem Biophys. 2000 Aug 1;380(1):1-10. doi: 10.1006/abbi.2000.1847.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。