Respiratory Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham B95SS, UK.
Institute of Applied Health Research, University of Birmingham, Birmingham B152TT, UK.
Medicina (Kaunas). 2019 Jun 15;55(6):277. doi: 10.3390/medicina55060277.
Current evidence suggests that patients with chronic obstructive pulmonary disease (COPD) should receive influenza and pneumococcal vaccinations. Despite international guidelines recommending vaccination in patients with COPD, many patients remain unvaccinated. Reasons for vaccine non-acceptance are multifaceted and are likely to be influenced by multiple psychosocial factors and pre-existing health beliefs. The aim of this review was to identify interventions which have been shown to effectively increase vaccination rates in patients with COPD. A structured search of PubMed returned 491 titles. Following title and abstract screening, seven full-text articles reporting on 6 unique interventional studies were extracted for narrative synthesis. A variety of interventions were investigated which, for the purposes of this review, were grouped into patient-focussed, clinician-focussed and mixed interventions. Three papers reported findings from clinical trials (2 unique studies) and 4 papers reported findings from before-after studies. Two studies were conducted in the primary care setting, the remaining studies were conducted in secondary and tertiary care. Most studies reported both influenza and pneumococcal vaccination rates. These studies suggest that multimodal interventions, which target multiple aspects of evidence-based care and use both patient-focussed and clinician-focussed techniques, may have the greatest impact on vaccination rates in patients with COPD. Further, adequately powered, high quality studies are needed. It is crucial for individual institutions to monitor their own vaccination rates to determine if there is scope for performance improvement.
目前的证据表明,慢性阻塞性肺疾病(COPD)患者应接种流感疫苗和肺炎球菌疫苗。尽管国际指南建议 COPD 患者接种疫苗,但仍有许多患者未接种。疫苗接种不被接受的原因是多方面的,可能受到多种社会心理因素和预先存在的健康信念的影响。本综述的目的是确定已被证明能有效提高 COPD 患者疫苗接种率的干预措施。通过对 PubMed 进行结构化搜索,共返回 491 个标题。在标题和摘要筛选后,提取了 7 篇全文报告 6 项独特干预研究的文章进行叙述性综合。研究了各种干预措施,为方便起见,这些干预措施分为以患者为中心、以临床医生为中心和混合干预措施。有 3 篇论文报告了临床试验的结果(2 项独特的研究),4 篇论文报告了前后对照研究的结果。两项研究在初级保健环境中进行,其余研究在二级和三级保健中进行。大多数研究报告了流感和肺炎球菌疫苗接种率。这些研究表明,针对循证护理多个方面的多模式干预措施,同时使用以患者为中心和以临床医生为中心的技术,可能对 COPD 患者的疫苗接种率产生最大影响。此外,还需要进行充分的、高质量的研究。各机构监测自己的疫苗接种率以确定是否有改进的空间至关重要。