Jabłońska S, Błaszczyk M, Górkiewicz A, Jarzabek-Chorzelska M, Rzesa G, Chorzelski T
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):765-8.
Antibodies against nuclear ribonucleoprotein (RNP) were found in 5 of 63 cases of systemic scleroderma, whereas they were present in all but one case of mixed connective tissue disease and in 15 of 67 cases of systemic lupus erythematosus. In all RNP positive cases of systemic scleroderma there were some features of other collagen diseases, and their course was relatively more benign. Studies of RNP antibodies in systemic scleroderma may be of importance for treatment and prognosis.
在63例系统性硬化症患者中，有5例检测出抗核糖核蛋白（RNP）抗体；而在除1例之外的所有混合性结缔组织病患者以及67例系统性红斑狼疮患者中的15例中也检测到了该抗体。在所有RNP抗体呈阳性的系统性硬化症病例中，均存在一些其他胶原病的特征，且其病程相对较为良性。对系统性硬化症中RNP抗体的研究可能对治疗和预后具有重要意义。
