• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

家族糖尿病史与健康行为依从性聚类之间的关联:来自健康体检者-基因(HEXA-G)研究的横断面结果。

Association between family history of diabetes and clusters of adherence to healthy behaviors: cross-sectional results from the Health Examinees-Gem (HEXA-G) study.

机构信息

Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.

出版信息

BMJ Open. 2019 Jun 16;9(6):e025477. doi: 10.1136/bmjopen-2018-025477.

DOI:10.1136/bmjopen-2018-025477
PMID:31209083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6588964/
Abstract

OBJECTIVES

This study evaluated whether individuals with affected family member adhered to healthy behaviours.

DESIGN AND SETTING

This was a cross-sectional study of participants selected from health examinees who underwent the national health check-up programme of Korea in 39 centres between 2004 and 2013.

PARTICIPANTS

The baseline data of 128 520 participants enrolled in the Health Examinees-Gem study were used for analysis.

MAIN OUTCOMES AND MEASURES

Associations of family history of diabetes with adherence to regular exercise, healthy diet and body composition, and clusters of healthy behaviours were evaluated while adjusting for potential confounders selected by a directed acyclic graph.

RESULTS

Participants with a family history of diabetes were more likely to adhere to a regular exercise regimen (OR=1.12, 95% CI 1.06 to 1.18 for men and OR=1.10, 95% CI 1.07 to 1.14 for women) and healthy diet (OR=1.06, 95% CI 1.01 to 1.12 for men and OR=1.06, 95% CI 1.01 to 1.12 for women) but were less likely to have a normal body composition (OR=0.83, 95% CI 0.78 to 0.87 for men and OR=0.83, 95% CI 0.80 to 0.86 for women). These associations were strengthened when the affected family members were siblings, the number of affected members was increased or the age at diagnosis of the affected member was younger than 50 years. In men and women, having a normal body composition is important in determining the cluster of behaviours, and those with a family history of diabetes were less likely to adhere to the normal body composition cluster.

CONCLUSIONS

The group with high risk of diabetes showed healthy behaviors, but they did not have a normal body composition. Policies and campaigns targeting integrated health behaviors will be needed to reduce the burden of diseases and improve public health.

摘要

目的

本研究旨在评估是否有家族成员患病的个体能够坚持健康行为。

设计与设置

这是一项横断面研究,参与者选自于 2004 年至 2013 年间在韩国 39 个中心接受国家健康检查计划的体检者。

参与者

使用了参加健康体检者-宝石研究的 128520 名参与者的基线数据进行分析。

主要结果和措施

在调整潜在混杂因素(由有向无环图选择)后,评估了糖尿病家族史与定期运动、健康饮食和身体成分以及健康行为群集的相关性。

结果

有糖尿病家族史的参与者更有可能坚持定期运动(男性 OR=1.12,95%CI 1.06 至 1.18;女性 OR=1.10,95%CI 1.07 至 1.14)和健康饮食(男性 OR=1.06,95%CI 1.01 至 1.12;女性 OR=1.06,95%CI 1.01 至 1.12),但更有可能出现异常的身体成分(男性 OR=0.83,95%CI 0.78 至 0.87;女性 OR=0.83,95%CI 0.80 至 0.86)。当受影响的家庭成员为兄弟姐妹、受影响的成员数量增加或受影响成员的诊断年龄小于 50 岁时,这些关联会得到加强。在男性和女性中,保持正常的身体成分对于确定行为群集很重要,而有糖尿病家族史的人不太可能坚持正常的身体成分群集。

结论

有较高糖尿病风险的人群表现出健康行为,但他们的身体成分并不正常。需要制定针对综合健康行为的政策和运动,以减轻疾病负担并改善公共卫生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d84/6588964/4bfbb9b3679d/bmjopen-2018-025477f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d84/6588964/6d823cc6b29f/bmjopen-2018-025477f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d84/6588964/4bfbb9b3679d/bmjopen-2018-025477f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d84/6588964/6d823cc6b29f/bmjopen-2018-025477f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d84/6588964/4bfbb9b3679d/bmjopen-2018-025477f02.jpg

相似文献

1
Association between family history of diabetes and clusters of adherence to healthy behaviors: cross-sectional results from the Health Examinees-Gem (HEXA-G) study.家族糖尿病史与健康行为依从性聚类之间的关联:来自健康体检者-基因(HEXA-G)研究的横断面结果。
BMJ Open. 2019 Jun 16;9(6):e025477. doi: 10.1136/bmjopen-2018-025477.
2
Identification of Risk Factors Affecting Impaired Fasting Glucose and Diabetes in Adult Patients from Northeast China.中国东北地区成年患者空腹血糖受损和糖尿病相关危险因素的识别
Int J Environ Res Public Health. 2015 Oct 12;12(10):12662-78. doi: 10.3390/ijerph121012662.
3
Factors associated with medication adherence among people with diabetes mellitus in poor urban areas of Cambodia: A cross-sectional study.柬埔寨贫困城区糖尿病患者药物治疗依从性的影响因素:一项横断面研究。
PLoS One. 2019 Nov 19;14(11):e0225000. doi: 10.1371/journal.pone.0225000. eCollection 2019.
4
Diabetes-related behaviours among elderly people with pre-diabetes in rural communities of Hunan, China: a cross-sectional study.中国湖南农村社区老年糖尿病前期患者的糖尿病相关行为:一项横断面研究
BMJ Open. 2018 Jan 23;8(1):e015747. doi: 10.1136/bmjopen-2016-015747.
5
Family history of diabetes, awareness of risk factors, and health behaviors among African Americans.非裔美国人的糖尿病家族史、危险因素认知及健康行为
Am J Public Health. 2007 May;97(5):907-12. doi: 10.2105/AJPH.2005.077032. Epub 2007 Mar 29.
6
Relationships among medication adherence, lifestyle modification, and health-related quality of life in patients with acute myocardial infarction: a cross-sectional study.急性心肌梗死患者药物依从性、生活方式改变与健康相关生活质量的关系:一项横断面研究。
Health Qual Life Outcomes. 2018 May 22;16(1):100. doi: 10.1186/s12955-018-0921-z.
7
Influence of familial risk on diabetes risk-reducing behaviors among U.S. adults without diabetes.家族患病史对美国无糖尿病成年人降低糖尿病风险行为的影响。
Diabetes Care. 2011 Nov;34(11):2393-9. doi: 10.2337/dc11-0876. Epub 2011 Sep 20.
8
Clustering patterns of obesity-related multiple lifestyle behaviours and their associations with overweight and family environments: a cross-sectional study in Japanese preschool children.肥胖相关多种生活方式行为的聚类模式及其与超重和家庭环境的关联:一项针对日本学龄前儿童的横断面研究
BMJ Open. 2016 Nov 4;6(11):e012773. doi: 10.1136/bmjopen-2016-012773.
9
Is family history related to preventive health behaviors and medical management in breast cancer patients?家族病史与乳腺癌患者的预防性健康行为及医疗管理有关吗?
Breast Cancer Res Treat. 2005 Mar;90(1):47-54. doi: 10.1007/s10549-004-2626-8.
10
Association between family history of diabetes and cardiovascular disease and lifestyle risk factors in the United States population: The 2009-2012 National Health and Nutrition Examination Survey.美国人群中糖尿病家族史与心血管疾病及生活方式风险因素之间的关联:2009 - 2012年国家健康与营养检查调查
Prev Med. 2017 Mar;96:129-134. doi: 10.1016/j.ypmed.2016.12.015. Epub 2016 Dec 19.

引用本文的文献

1
Psychological resilience, resilient coping, and health behaviors among adults in Puerto Rico after multiple adverse events.波多黎各成年人在经历多次不良事件后的心理韧性、适应性应对及健康行为
Prev Med Rep. 2024 Aug 30;46:102874. doi: 10.1016/j.pmedr.2024.102874. eCollection 2024 Oct.
2
Social Determinants of Health Phenotypes and Cardiometabolic Condition Prevalence Among Patients in a Large Academic Health System: Latent Class Analysis.大型学术医疗系统中患者健康表型的社会决定因素与心血管代谢疾病患病率:潜在类别分析
JMIR Public Health Surveill. 2024 Aug 7;10:e53371. doi: 10.2196/53371.
3
Pros and cons of live kidney donation in prediabetics: A critical review and way forward.

本文引用的文献

1
Who perceives a higher personal risk of developing type 2 diabetes? A cross-sectional study on associations between personality traits, health-related behaviours and perceptions of susceptibility among university students in Denmark.谁认为自己患 2 型糖尿病的个人风险更高?一项关于丹麦大学生人格特质、健康相关行为与易感性认知之间关系的横断面研究。
BMC Public Health. 2018 Aug 4;18(1):972. doi: 10.1186/s12889-018-5884-9.
2
An association between diet quality index for Koreans (DQI-K) and total mortality in Health Examinees Gem (HEXA-G) study.韩国人饮食质量指数(DQI-K)与健康体检者队列研究(HEXA-G)中的全因死亡率之间的关联。
Nutr Res Pract. 2018 Jun;12(3):258-264. doi: 10.4162/nrp.2018.12.3.258. Epub 2018 May 23.
3
糖尿病前期患者活体肾捐赠的利弊:一项批判性综述及未来方向
World J Transplant. 2024 Mar 18;14(1):89822. doi: 10.5500/wjt.v14.i1.89822.
4
Dietary Knowledge and Eating Habits among Patients with Type 2 Diabetes in Lebanon.黎巴嫩 2 型糖尿病患者的饮食知识和饮食习惯。
Glob Health Epidemiol Genom. 2024 Feb 6;2024:3623555. doi: 10.1155/2024/3623555. eCollection 2024.
5
Moderating Effect of Grip Strength in the Association between Diabetes Mellitus and Depressive Symptomatology.握力在糖尿病与抑郁症状关联中的调节作用
Sports (Basel). 2023 Dec 20;12(1):3. doi: 10.3390/sports12010003.
6
Timely referral to health centers for the prevention of cardiovascular diseases: IraPEN national program.及时转介至保健中心预防心血管疾病:IraPEN 国家计划。
Front Public Health. 2023 Sep 22;11:1098312. doi: 10.3389/fpubh.2023.1098312. eCollection 2023.
7
Association Between Family History of Diabetes, Irrational Beliefs, and Health Anxiety with 10-Year Risk of Type 2 Diabetes Mellitus: the ATTICA Epidemiological Study (2002-2012).家族糖尿病史、不合理信念与健康焦虑与 10 年 2 型糖尿病发病风险的关系:ATTICA 流行病学研究(2002-2012 年)。
Int J Behav Med. 2024 Aug;31(4):516-526. doi: 10.1007/s12529-023-10189-8. Epub 2023 Jun 15.
8
Interleukin-39 is a novel cytokine associated with type 2 diabetes mellitus and positively correlated with body mass index.白细胞介素-39 是一种与 2 型糖尿病相关的新型细胞因子,与体重指数呈正相关。
Endocrinol Diabetes Metab. 2023 May;6(3):e409. doi: 10.1002/edm2.409. Epub 2023 Feb 9.
9
Interaction analysis of lipid accumulation product and family history of diabetes on impaired fasting glucose and diabetes risk in population with normotension in Eastern China: a community-based cross-sectional survey.中国东部正常血压人群中脂质积聚产物与糖尿病家族史对空腹血糖受损及糖尿病风险的交互作用分析:一项基于社区的横断面调查
Arch Public Health. 2022 Oct 1;80(1):217. doi: 10.1186/s13690-022-00972-6.
10
Healthful Plant-Based Diet and Incidence of Type 2 Diabetes in Asian Population.植物性健康饮食与亚洲人群 2 型糖尿病的发病风险
Nutrients. 2022 Jul 27;14(15):3078. doi: 10.3390/nu14153078.
Cohort Profile: The Korean Genome and Epidemiology Study (KoGES) Consortium.
队列简介:韩国基因组与流行病学研究(KoGES)联盟。
Int J Epidemiol. 2017 Aug 1;46(4):1350. doi: 10.1093/ije/dyx105.
4
Type 2 diabetes in adolescents and young adults.青少年和年轻成人 2 型糖尿病。
Lancet Diabetes Endocrinol. 2018 Jan;6(1):69-80. doi: 10.1016/S2213-8587(17)30186-9. Epub 2017 Aug 25.
5
Adherence to a healthy lifestyle and the risk of type 2 diabetes in Chinese adults.中国成年人坚持健康的生活方式与 2 型糖尿病风险的关系。
Int J Epidemiol. 2017 Oct 1;46(5):1410-1420. doi: 10.1093/ije/dyx074.
6
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.肥胖症中全基因组身体活动相互作用——对200452名成年人的荟萃分析
PLoS Genet. 2017 Apr 27;13(4):e1006528. doi: 10.1371/journal.pgen.1006528. eCollection 2017 Apr.
7
Association between family history of diabetes and cardiovascular disease and lifestyle risk factors in the United States population: The 2009-2012 National Health and Nutrition Examination Survey.美国人群中糖尿病家族史与心血管疾病及生活方式风险因素之间的关联:2009 - 2012年国家健康与营养检查调查
Prev Med. 2017 Mar;96:129-134. doi: 10.1016/j.ypmed.2016.12.015. Epub 2016 Dec 19.
8
Standards of Medical Care in Diabetes-2017: Summary of Revisions.《2017年糖尿病医疗护理标准:修订摘要》
Diabetes Care. 2017 Jan;40(Suppl 1):S4-S5. doi: 10.2337/dc17-S003.
9
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.1990 - 2015年全球、区域和国家310种疾病和损伤的发病率、患病率及伤残调整生命年:全球疾病负担研究2015的系统分析
Lancet. 2016 Oct 8;388(10053):1545-1602. doi: 10.1016/S0140-6736(16)31678-6.
10
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.1980 - 2015年全球、区域和国家249种死因的预期寿命、全死因死亡率和死因别死亡率:全球疾病负担研究2015的系统分析
Lancet. 2016 Oct 8;388(10053):1459-1544. doi: 10.1016/S0140-6736(16)31012-1.