Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea.
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
BMJ Open. 2019 Jun 16;9(6):e025477. doi: 10.1136/bmjopen-2018-025477.
This study evaluated whether individuals with affected family member adhered to healthy behaviours.
This was a cross-sectional study of participants selected from health examinees who underwent the national health check-up programme of Korea in 39 centres between 2004 and 2013.
The baseline data of 128 520 participants enrolled in the Health Examinees-Gem study were used for analysis.
Associations of family history of diabetes with adherence to regular exercise, healthy diet and body composition, and clusters of healthy behaviours were evaluated while adjusting for potential confounders selected by a directed acyclic graph.
Participants with a family history of diabetes were more likely to adhere to a regular exercise regimen (OR=1.12, 95% CI 1.06 to 1.18 for men and OR=1.10, 95% CI 1.07 to 1.14 for women) and healthy diet (OR=1.06, 95% CI 1.01 to 1.12 for men and OR=1.06, 95% CI 1.01 to 1.12 for women) but were less likely to have a normal body composition (OR=0.83, 95% CI 0.78 to 0.87 for men and OR=0.83, 95% CI 0.80 to 0.86 for women). These associations were strengthened when the affected family members were siblings, the number of affected members was increased or the age at diagnosis of the affected member was younger than 50 years. In men and women, having a normal body composition is important in determining the cluster of behaviours, and those with a family history of diabetes were less likely to adhere to the normal body composition cluster.
The group with high risk of diabetes showed healthy behaviors, but they did not have a normal body composition. Policies and campaigns targeting integrated health behaviors will be needed to reduce the burden of diseases and improve public health.
本研究旨在评估是否有家族成员患病的个体能够坚持健康行为。
这是一项横断面研究,参与者选自于 2004 年至 2013 年间在韩国 39 个中心接受国家健康检查计划的体检者。
使用了参加健康体检者-宝石研究的 128520 名参与者的基线数据进行分析。
在调整潜在混杂因素(由有向无环图选择)后,评估了糖尿病家族史与定期运动、健康饮食和身体成分以及健康行为群集的相关性。
有糖尿病家族史的参与者更有可能坚持定期运动(男性 OR=1.12,95%CI 1.06 至 1.18;女性 OR=1.10,95%CI 1.07 至 1.14)和健康饮食(男性 OR=1.06,95%CI 1.01 至 1.12;女性 OR=1.06,95%CI 1.01 至 1.12),但更有可能出现异常的身体成分(男性 OR=0.83,95%CI 0.78 至 0.87;女性 OR=0.83,95%CI 0.80 至 0.86)。当受影响的家庭成员为兄弟姐妹、受影响的成员数量增加或受影响成员的诊断年龄小于 50 岁时,这些关联会得到加强。在男性和女性中,保持正常的身体成分对于确定行为群集很重要,而有糖尿病家族史的人不太可能坚持正常的身体成分群集。
有较高糖尿病风险的人群表现出健康行为,但他们的身体成分并不正常。需要制定针对综合健康行为的政策和运动,以减轻疾病负担并改善公共卫生。