Lange A, Smolik R, Chmielarczyk W, Garncarek D, Gielgier Z
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):881-5.
Clustering of ANA and SMA was evaluated in patients with various internal diseases as a pattern of autoantibody formation. SMA was found in ANA positive patients with chronic hepatitis, undefined collagenoses and autoallergic thyroid diseases significantly more frequently, than in patients without any autoallergic disorders. The incidence of SMA in ANA positive cases with SLE and RA did not exceed their predictable by chance incidence. It was not found that clustering of autoantibodies is correlated with the E and C lymphocyte receptor abnormality as compared to the control group. The lowest count of E-RFC was found in SLE cases which differed significantly in this respect from the control group and also from chronic vasculitis cases. The clustering of autoantibodies is not correlated with hyperimmunoglobulinemia.
在患有各种内科疾病的患者中，评估了抗核抗体（ANA）和抗平滑肌抗体（SMA）的聚集情况，以此作为自身抗体形成的一种模式。在患有慢性肝炎、未明确的胶原病和自身免疫性甲状腺疾病的ANA阳性患者中，发现SMA的出现频率明显高于无任何自身免疫性疾病的患者。在系统性红斑狼疮（SLE）和类风湿关节炎（RA）的ANA阳性病例中，SMA的发生率未超过其偶然发生率的预期值。与对照组相比，未发现自身抗体的聚集与E和C淋巴细胞受体异常相关。在SLE病例中发现E玫瑰花结形成细胞（E-RFC）计数最低，在这方面与对照组以及慢性血管炎病例均有显著差异。自身抗体的聚集与高免疫球蛋白血症无关。
