Purdue University, West Lafayette, IN, USA.
J Speech Lang Hear Res. 2011 Jun;54(3):787-802. doi: 10.1044/1092-4388(2010/09-0085). Epub 2010 Nov 8.
To investigate the effects of increased syntactic complexity and utterance length demands on speech production and comprehension in individuals with Parkinson's disease (PD) using behavioral and physiological measures.
Speech response latency, interarticulatory coordinative consistency, accuracy of speech production, and response latency and accuracy on a receptive language task were analyzed in 16 individuals with PD and 16 matched control participants.
Individuals with PD had higher oral motor coordination variability, took a longer time to initiate speech, and made more errors on the speaking task compared with the control group. They also received lower scores on the 2 complex conditions of the receptive language task. Increased length and syntactic complexity negatively affected performance in both groups of speakers.
These findings provide a novel window into the speech deficits associated with PD by examining performance on longer, sentence-level utterances in contrast to earlier investigations of single-word or nonword productions. Speech motor control processes and language comprehension were adversely affected in the majority of our participants with mild to moderate PD compared to the control group. Finally, increased syntactic complexity and sentence length affected both the healthy aging and PD groups' speech production performance at the behavioral and kinematic levels.
使用行为和生理测量方法，研究增加句法复杂度和话语长度需求对帕金森病（PD）个体言语产生和理解的影响。
分析了 16 名 PD 患者和 16 名匹配的对照组参与者的言语反应时、发音间协调性一致性、言语产生的准确性以及接受性语言任务的反应时和准确性。
与对照组相比，PD 患者的口腔运动协调性变异性更高，言语起始时间更长，言语任务的错误更多。他们在接受性语言任务的 2 个复杂条件下的得分也较低。长度和句法复杂度的增加对两组说话者的表现都有负面影响。
这些发现通过对比单字或非字生成的早期研究，为检查长句层面的言语表现提供了一个研究 PD 相关言语缺陷的新窗口。与对照组相比，我们的大多数轻度至中度 PD 参与者的言语运动控制过程和语言理解受到了不利影响。最后，句法复杂度和句子长度的增加都影响了健康老年人和 PD 组在行为和运动学层面上的言语产生表现。
