Usui Yoshihiko, Goto Hiroshi
Department of Ophthalmology, Tokyo Medical University, Tokyo 160-0023, Japan.
Clin Ophthalmol. 2019 May 27;13:895-896. doi: 10.2147/OPTH.S200519. eCollection 2019.
Sarcoidosis is a multi-system disease characterized by the presence of non-caseating epithelioid granulomas in affected tissues and the most frequent cause of noninfectious uveitis in Japan. Ocular manifestations of sarcoid uveitis vary enormously and commonly characterized by granulomatous anterior uveitis, intermediate uveitis, and posterior uveitis such as retinal periphlebitis, choroiditis, optic nerve granuloma and papillitis. However, case reports of multiple granuloma formation related to sarcoid uveitis is uncommon. This report describes the use of optical coherence tomography angiography to visualize changes occurring in granuloma formation in deeper retinal plexus before and after systemic corticosteroid treatment.
结节病是一种多系统疾病,其特征是受累组织中存在非干酪样上皮样肉芽肿,是日本非感染性葡萄膜炎最常见的病因。结节性葡萄膜炎的眼部表现差异极大,通常表现为肉芽肿性前葡萄膜炎、中间葡萄膜炎和后葡萄膜炎,如视网膜静脉周围炎、脉络膜炎、视神经肉芽肿和视乳头炎。然而,与结节性葡萄膜炎相关的多个肉芽肿形成的病例报告并不常见。本报告描述了使用光学相干断层扫描血管造影术来观察全身皮质类固醇治疗前后视网膜深层神经丛中肉芽肿形成的变化。