Zou Sumeng, Ma Lingwei, Li Jianghao, Liu Yuehua, Zhao Dongliang, Zhang Zhengjun
State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, China.
Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing, China.
Front Chem. 2019 Jun 4;7:376. doi: 10.3389/fchem.2019.00376. eCollection 2019.
Surface-Enhanced Raman Scattering (SERS) is a powerful technology that provides abundant chemical fingerprint information with advantages of high sensitivity and time-saving. Advancements in SERS substrates fabrication allow Ag nanorods (AgNRs) possess superior sensitivity, high uniformity, and excellent reproducibility. To further promote AgNRs as a promising SERS substrate candidate to a broader application scope, oxides are integrated with AgNRs by virtue of their unique properties which endow the AgNRs-oxide hybrid with high stability and recyclability. Aside from SERS substrates fabrication, significant developments in quantitative analysis strategies offer enormous approaches to minimize influences resulted from variations of measuring conditions and to provide the reasonable data analysis. In this review, we discuss various fabrication approaches for AgNRs and AgNRs-oxide hybrids to achieve efficient SERS platforms. Then, we introduce three types of strategies which are commonly employed in chemical quantitative analysis to reach a reliable result. Further, we highlight SERS applications including food safety, environment safety, biosensing, and vapor sensing, demonstrating the potential of SERS as a powerful and promising technique. Finally, we conclude with the current challenges and future prospects toward efficient SERS manipulations for broader real-world applications.
表面增强拉曼散射（SERS）是一项强大的技术，具有高灵敏度和省时的优点，能提供丰富的化学指纹信息。SERS基底制备技术的进步使得银纳米棒（AgNRs）具有卓越的灵敏度、高均匀性和出色的可重复性。为了进一步推动AgNRs作为一种有前景的SERS基底候选材料应用于更广泛的领域，利用氧化物的独特性质将其与AgNRs相结合，使AgNRs - 氧化物复合材料具有高稳定性和可回收性。除了SERS基底制备，定量分析策略的重大进展提供了大量方法，可最大限度地减少测量条件变化带来的影响，并提供合理的数据分析。在本综述中，我们讨论了用于制备AgNRs和AgNRs - 氧化物复合材料以实现高效SERS平台的各种方法。然后，我们介绍了化学定量分析中常用的三种策略，以获得可靠的结果。此外，我们重点介绍了SERS在食品安全、环境安全、生物传感和气相传感等方面的应用，展示了SERS作为一种强大且有前景的技术的潜力。最后，我们总结了当前在实现更广泛实际应用的高效SERS操作方面面临的挑战和未来前景。
