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犬肾上腺神经母细胞瘤的手术切除

Surgical Excision of an Adrenal Neuroblastoma in a Dog.

作者信息

Mestrinho Lisa Alexandra, Marques Maria Inês, Jesus Sandra, Pissarra Hugo, Peleteiro Maria, Ferreira Antonio

机构信息

CIISA - Centre for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.

出版信息

Front Vet Sci. 2019 May 29;6:161. doi: 10.3389/fvets.2019.00161. eCollection 2019.

Abstract

A 11-month-old, intact male, Rhodesian Ridgeback was presented to the Veterinary Teaching Hospital with signs of inappetence, lethargy, and abdominal pain for 3 days. A large and well-defined abdominal retroperitoneal mass, related with the left kidney, at the expected location of the adrenal gland, was revealed by radiography, ultrasound, and computed tomography. The mass extended caudally to the iliac artery bifurcation, compressing the aorta, caudal vena cava, and both kidneys. Cytology findings were compatible with a malignant round cell tumor. The most probable diagnosis was neuroblastoma. Following a comprehensive discussion with the owners about a treatment plan, surgical excision was performed. Because a wide excision would compromise major vessels, excision was performed after careful dissection of the aorta and vena cava. The left kidney was removed because the proximal ureter could not be separated from the tumor. The animal recovered successfully. Diagnosis was confirmed by histopathology and immunohistochemistry, but the owners decided not to pursue any further treatment. Clinical signs of abdominal pain recurred within 1 month following surgery. Therefore, the animal was euthanized upon the owners' request. This report describes the diagnosis, surgical treatment, and follow-up of a dog with an abdominal peripheral neuroblastoma.

摘要

一只11个月大、未绝育的雄性罗德西亚脊背犬因食欲不振、嗜睡和腹痛症状被送至兽医教学医院,症状已持续3天。通过X光、超声和计算机断层扫描发现,在肾上腺预期位置有一个与左肾相关的、边界清晰的巨大腹膜后肿物。肿物向尾侧延伸至髂动脉分叉处,压迫主动脉、下腔静脉和双侧肾脏。细胞学检查结果与恶性圆形细胞瘤相符。最可能的诊断是神经母细胞瘤。在与主人就治疗方案进行全面讨论后,实施了手术切除。由于广泛切除会危及主要血管,因此在仔细解剖主动脉和腔静脉后进行了切除。由于近端输尿管无法与肿瘤分离,左肾被切除。该动物成功康复。组织病理学和免疫组化确诊了病情,但主人决定不再进行进一步治疗。术后1个月内,腹痛的临床症状再次出现。因此,应主人要求对该动物实施了安乐死。本报告描述了一只患有腹部周围神经母细胞瘤犬的诊断、手术治疗及随访情况。

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