Fu Ling, Sun Xiaochun, Gao Yumei, Chen Rui
College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650500, China.
J Am Soc Mass Spectrom. 2019 Aug;30(8):1545-1549. doi: 10.1007/s13361-019-02211-9. Epub 2019 Jun 18.
Accurate mass calibration is beneficial to the identification of the unknown compounds quickly and accurately. The ESI mass spectrum of tannic acid (TA) tends to a normal distribution of the cluster ion peaks in m/z range from 371.0368 to 1739.1169. Based on the interesting result, we reported the use of TA, a natural plant polyphenol, as a novel calibrator for electrospray ionization mass spectrometry (ESI MS), which has the following three advantages, including (1) easy preparation, (2) the calibration range of m/z 200~2000, and (3) the calibration error is around 3.00 ppm in positive ion mode, which is less than the use of sodium formate (SF) and Prod #88323 calibrators. This TA calibrator has great potential for the wide applications in biological, chemical, and pharmacal analysis.
准确的质量校准有利于快速、准确地鉴定未知化合物。单宁酸（TA）的电喷雾电离质谱（ESI-MS）在m/z范围为371.0368至1739.1169时，簇离子峰呈正态分布。基于这一有趣的结果，我们报道了使用天然植物多酚TA作为电喷雾电离质谱（ESI MS）的新型校准剂，它具有以下三个优点：（1）制备简单；（2）m/z 200~2000的校准范围；（3）在正离子模式下校准误差约为3.00 ppm，小于使用甲酸钠（SF）和Prod #88323校准剂。这种TA校准剂在生物、化学和药物分析的广泛应用中具有巨大潜力。
Zotero 插件