Kawakami Y, Abe S, Nishimura M, Araya Y, Wakabayashi O, Fujioka Y
First Department of Medicine, School of Medicine, Hokkaido University, Sapporo, Japan.
Jpn J Med. 1987 Aug;26(3):409-12. doi: 10.2169/internalmedicine1962.26.409.
A thirty-three-year-old man with diffuse pulmonary ossification associated with chronic bronchitis is described. Chest roentgenograms of the patient showed diffuse reticulo-nodular shadows partially super-imposed by calcified reticular opacities. Marked declines in forced vital capacity and air-flow limitation were associated with decreased diffusing capacity of the lung for CO, hypoxemia, and hypercapnia. In the postmortem examination, diffuse dendriform ossification was found mainly in the alveolar space. Neither interstitial fibrosis nor capillary congestion was found histopathologically in the lung.
本文描述了一名33岁患有弥漫性肺骨化并伴有慢性支气管炎的男性患者。患者的胸部X线片显示弥漫性网状结节阴影，部分被钙化的网状混浊影叠加。用力肺活量和气流受限显著下降，同时伴有肺一氧化碳弥散能力降低、低氧血症和高碳酸血症。尸检发现，弥漫性树枝状骨化主要存在于肺泡腔内。在组织病理学上，肺部未发现间质纤维化或毛细血管充血。
