Sun Yankai, Overby Philip J, Mehta Hasit
From the Section on Neuroradiology, Department of Radiology (Y.S., H.M.), and Section on Pediatric Neurology, Department of Pediatrics (P.J.O.), New York Medical College, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595.
Radiology. 2019 Jul;292(1):259-262. doi: 10.1148/radiol.2019170925.
History An 11-year-old boy taking oral antibiotics for meningitis diagnosed 3 months earlier presented to the emergency department with a 1-week history of intermittent emesis, dizziness, and vertigo and a 1-day history of wobbly gait and bilateral lower extremity paresthesia without confusion. His metabolic profile was normal. Contrast material-enhanced MRI of the brain was performed, and selected images are shown ( Fig 1 - 4 ). Figure 1a: Axial fluid-attenuated inversion recovery (repetition time msec/echo time msec, 11 000/125) MRI and axial turbo spin-echo T2-weighted (3000/80) MRI of the brain through the cerebellum at presentation. Axial fluid-attenuated inversion recovery (6000/120) MRI and axial turbo spin-echo T2-weighted (5545/100) MRI through the same level of the cerebellum obtained 6 weeks earlier. Figure 1b: Axial fluid-attenuated inversion recovery (repetition time msec/echo time msec, 11 000/125) MRI and axial turbo spin-echo T2-weighted (3000/80) MRI of the brain through the cerebellum at presentation. Axial fluid-attenuated inversion recovery (6000/120) MRI and axial turbo spin-echo T2-weighted (5545/100) MRI through the same level of the cerebellum obtained 6 weeks earlier. Figure 1c: Axial fluid-attenuated inversion recovery (repetition time msec/echo time msec, 11 000/125) MRI and axial turbo spin-echo T2-weighted (3000/80) MRI of the brain through the cerebellum at presentation. Axial fluid-attenuated inversion recovery (6000/120) MRI and axial turbo spin-echo T2-weighted (5545/100) MRI through the same level of the cerebellum obtained 6 weeks earlier. Figure 1d: Axial fluid-attenuated inversion recovery (repetition time msec/echo time msec, 11 000/125) MRI and axial turbo spin-echo T2-weighted (3000/80) MRI of the brain through the cerebellum at presentation. Axial fluid-attenuated inversion recovery (6000/120) MRI and axial turbo spin-echo T2-weighted (5545/100) MRI through the same level of the cerebellum obtained 6 weeks earlier. Figure 2a: Axial fast spin-echo T1-weighted MRI (496/8) and axial reconstruction of three-dimensional fast field-echo T1-weighted contrast-enhanced (7 mL of gadobutrol, Gadavist; Bayer Healthcare Pharmaceuticals, Berlin, Germany) MRI (7.98/3.72) of regions similar to those in Figure 1 . Figure 2b: Axial fast spin-echo T1-weighted MRI (496/8) and axial reconstruction of three-dimensional fast field-echo T1-weighted contrast-enhanced (7 mL of gadobutrol, Gadavist; Bayer Healthcare Pharmaceuticals, Berlin, Germany) MRI (7.98/3.72) of regions similar to those in Figure 1 . Figure 3a: Axial diffusion-weighted MRI (3090/71) and axial apparent diffusion coefficient map (3090/71) of regions similar to those in Figure 1 . Figure 3b: Axial diffusion-weighted MRI (3090/71) and axial apparent diffusion coefficient map (3090/71) of regions similar to those in Figure 1 . Figure 4: Three-dimensional maximum intensity projection image (25/3.45) of the posterior cerebral circulation obtained with MR angiography of the head.
病史 一名11岁男孩,3个月前被诊断为脑膜炎,一直在口服抗生素治疗,现因1周的间歇性呕吐、头晕和眩晕病史以及1天的步态不稳和双侧下肢感觉异常(无神志不清)就诊于急诊科。他的代谢指标正常。进行了脑部对比剂增强MRI检查,部分图像见图1 - 4。图1a:就诊时通过小脑层面的脑部轴位液体衰减反转恢复序列(重复时间毫秒/回波时间毫秒,11000/125)MRI和轴位快速自旋回波T2加权(3000/80)MRI。6周前通过小脑同一层面的轴位液体衰减反转恢复序列(6000/120)MRI和轴位快速自旋回波T2加权(5545/100)MRI。图1b:就诊时通过小脑层面的脑部轴位液体衰减反转恢复序列(重复时间毫秒/回波时间毫秒,11000/125)MRI和轴位快速自旋回波T2加权(3000/80)MRI。6周前通过小脑同一层面的轴位液体衰减反转恢复序列(6000/120)MRI和轴位快速自旋回波T2加权(5545/100)MRI。图1c:就诊时通过小脑层面的脑部轴位液体衰减反转恢复序列(重复时间毫秒/回波时间毫秒,11000/125)MRI和轴位快速自旋回波T2加权(3000/80)MRI。6周前通过小脑同一层面的轴位液体衰减反转恢复序列(6000/120)MRI和轴位快速自旋回波T2加权(5545/100)MRI。图1d:就诊时通过小脑层面的脑部轴位液体衰减反转恢复序列(重复时间毫秒/回波时间毫秒,11000/125)MRI和轴位快速自旋回波T2加权(3000/80)MRI。6周前通过小脑同一层面的轴位液体衰减反转恢复序列(6000/120)MRI和轴位快速自旋回波T2加权(5545/100)MRI。图2a:与图1类似区域的轴位快速自旋回波T1加权MRI(496/8)和三维快速场回波T1加权对比增强(7毫升钆布醇,佳迪显;拜耳医疗保健制药公司,德国柏林)MRI的轴向重建(7.98/3.72)。图2b:与图1类似区域的轴位快速自旋回波T1加权MRI(496/8)和三维快速场回波T1加权对比增强(7毫升钆布醇,佳迪显;拜耳医疗保健制药公司,德国柏林)MRI的轴向重建(7.98/3.72)。图3a:与图1类似区域的轴位扩散加权MRI(3090/71)和轴位表观扩散系数图(3090/71)。图3b:与图1类似区域的轴位扩散加权MRI(3090/71)和轴位表观扩散系数图(3090/71)。图4:头部MR血管造影获得的大脑后循环三维最大强度投影图像(25/3.45)。