Czerny C, Rand T, Gstoettner W, Woelfl G, Imhof H, Trattnig S
Department of Radiology, University of Vienna, Austria.
AJR Am J Roentgenol. 1998 Mar;170(3):791-6. doi: 10.2214/ajr.170.3.9490977.
The aim of the study was to compare the ability of three-dimensional (3D) T2-weighted turbo spin-echo and gadolinium-enhanced 3D T1-weighted gradient-echo sequences with two-dimensional (2D) T2-weighted turbo spin-echo and gadolinium-enhanced T1-weighted spin-echo sequences to reveal anatomic and pathologic structures of the inner ear and cerebellopontine angle.
Thirty-one patients underwent axial 2D T2-weighted turbo spin-echo and 3D T2-weighted turbo spin-echo MR imaging, axial and coronal 2D T1-weighted spin-echo MR imaging before and after i.v. injection of gadopentetate dimeglumine, and gadolinium-enhanced axial 3D T1-weighted gradient-echo MR imaging. The visualization of anatomic and pathologic structures on the different sequences was evaluated. Statistical analysis was performed from the data obtained from the visual evaluation of the anatomic structures on the different sequences. Signal-to-noise and contrast-to-noise ratios were calculated for the gadolinium-enhanced 3D T1-weighted gradient-echo and 2D T1-weighted spin-echo sequences, and statistical evaluation was performed.
The 3D sequences enabled excellent visualization of 94% of all evaluated anatomic structures, and the 2D sequences enabled excellent visualization in only 3% of these structures. Pathologic structures were revealed in all cases by one or both of the 3D sequences. Diagnosis in all patients could be made by using the combination of the 3D T2-weighted turbo spin-echo and the gadolinium-enhanced 3D T1-weighted gradient-echo sequences. However, the 2D sequences failed to show pathologic structures in three patients. We found a significant statistical difference for the visualization of anatomic structures with the 3D and 2D sequences (p < .0001) and no significant statistical difference for the signal-to-noise and contrast-to-noise ratios with the 3D T1-weighted gradient-echo and 2D T1-weighted spin-echo sequences.
The 3D sequences revealed anatomic structures significantly better than did the 2D sequences and showed pathologic structures considerably more often than did the 2D sequences in all patients. MR imaging of the inner ear and cerebellopontine angle performed with 3D T2-weighted turbo spin-echo and gadolinium-enhanced 3D T1-weighted gradient-echo sequences provided the most accurate imaging leading to diagnosis in cases of abnormality.
本研究旨在比较三维（3D）T2加权快速自旋回波序列和钆增强三维T1加权梯度回波序列与二维（2D）T2加权快速自旋回波序列和钆增强T1加权自旋回波序列显示内耳及桥小脑角解剖和病理结构的能力。
31例患者接受了轴位二维T2加权快速自旋回波和三维T2加权快速自旋回波磁共振成像、静脉注射钆喷酸葡胺前后的轴位和冠状位二维T1加权自旋回波磁共振成像，以及钆增强轴位三维T1加权梯度回波磁共振成像。评估不同序列上解剖和病理结构的显示情况。对不同序列上解剖结构视觉评估获得的数据进行统计分析。计算钆增强三维T1加权梯度回波序列和二维T1加权自旋回波序列的信噪比和对比噪声比，并进行统计评估。
三维序列能清晰显示94%的所有评估解剖结构，而二维序列仅能清晰显示其中3%的结构。在所有病例中，一种或两种三维序列均能显示病理结构。所有患者均通过三维T2加权快速自旋回波序列和钆增强三维T1加权梯度回波序列的联合使用得以确诊。然而，二维序列在3例患者中未能显示病理结构。我们发现三维和二维序列在解剖结构显示方面存在显著统计学差异（p <.0001），而三维T1加权梯度回波序列和二维T1加权自旋回波序列在信噪比和对比噪声比方面无显著统计学差异。
在所有患者中，三维序列显示解剖结构明显优于二维序列，显示病理结构的频率也远高于二维序列。采用三维T2加权快速自旋回波序列和钆增强三维T1加权梯度回波序列对内耳及桥小脑角进行磁共振成像，能提供最准确的成像，有助于异常情况的诊断。
