Trent Oesophago-Gastric Unit, Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK.
NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham , Nottingham, UK.
World J Surg. 2019 Oct;43(10):2483-2489. doi: 10.1007/s00268-019-05057-0.
Several techniques have been described for esophagogastric anastomosis following esophagectomy. This study compared the outcomes of circular stapled anastomoses with semi-mechanical technique using a linear stapler.
Perioperative data were extracted from a contemporaneously collected database of all consecutive esophagectomies for cancer with intrathoracic anastomoses performed in the Trent Oesophago-Gastric Unit between January 2015 and April 2018. Anastomotic techniques: circular stapled versus semi-mechanical, were evaluated and outcomes were compared. The primary outcome was anastomotic leak rate. Secondary outcomes included anastomotic stricture, overall complication rates, length of stay (LOS) and 30 day all-cause mortality.
One hundred and fifty-nine consecutive esophagectomies with intrathoracic anastomosis were performed during the study period. There were no significant differences between the two groups in terms of age, American Society of Anaesthesiologists score, Charlson comorbidity index and neoadjuvant therapies received. Circular stapled anastomoses were performed in 85 patients, while 74 patients received a semi-mechanical anastomosis. Clavien-Dindo complications II or more were higher in the circular stapled group (p = 0.02). There were 16 (10%) anastomotic leaks overall, three (4%) in semi-mechanical group versus 13 (15%) in the circular stapled group (p < 0.019). There was no statistically significant difference between the two groups in terms of LOS, 30-day mortality or the need for endoscopic dilatation of the anastomosis at 3 months follow-up.
The move from a circular stapled to a semi-mechanical intrathoracic anastomosis has been associated with a reduced postoperative anastomotic leak rate following esophagectomy for esophageal cancer.
几种技术已被描述用于食管癌切除术后的食管胃吻合术。本研究比较了使用线性吻合器的圆形吻合与半机械技术的结果。
从 2015 年 1 月至 2018 年 4 月期间在特伦特食管胃单位进行的所有连续食管癌开胸吻合术的同期收集数据库中提取围手术期数据。评估吻合技术:圆形吻合与半机械吻合,并比较结果。主要结果是吻合口漏率。次要结果包括吻合口狭窄、总并发症发生率、住院时间(LOS)和 30 天全因死亡率。
在研究期间,进行了 159 例连续开胸食管癌吻合术。两组患者在年龄、美国麻醉医师协会评分、Charlson 合并症指数和接受的新辅助治疗方面无显著差异。85 例患者行圆形吻合,74 例患者行半机械吻合。圆形吻合组 Clavien-Dindo 并发症 II 级或更高的发生率较高(p=0.02)。总的吻合口漏发率为 16%(10%),半机械组 3 例(4%),圆形吻合组 13 例(15%)(p<0.019)。两组在 LOS、30 天死亡率或 3 个月随访时需要内镜扩张吻合口方面无统计学差异。
从圆形吻合到半机械开胸吻合的转变与食管癌切除术后术后吻合口漏率降低有关。