Department of Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 60167, Mannheim, Germany.
Langenbecks Arch Surg. 2022 Aug;407(5):1831-1838. doi: 10.1007/s00423-022-02590-w. Epub 2022 Jun 22.
Current data states that most likely there are differences in postoperative complications regarding linear and circular stapling in open esophagectomy. This, however, has not yet been summarized and overviewed for minimally invasive esophagectomy, which is being performed increasingly.
A pooled analysis was conducted, including 4 publications comparing linear and circular stapling techniques in minimally invasive esophagectomy (MIE) and robotic-assisted minimally invasive esophagectomy (RAMIE). Primary endpoints were anastomotic leakage, pulmonary complications, and mean hospital stay.
Summarizing the 4 chosen publications, no difference in anastomotic insufficiency could be displayed (p = 0.34). Similar results were produced for postoperative pulmonary complications. Comparing circular stapling (CS) to linear stapling (LS) did not show a trend towards a favorable technique (p = 0.82). Some studies did not take learning curves into account. Postoperative anastomotic stricture was not specified to an extent that made a summary of the publications possible.
In conclusion, data is not sufficient to provide a differentiated recommendation towards mechanical stapling techniques for individual patients undergoing MIE and RAMIE. Therefore, further RCTs are necessary for the identification of potential differences between LS and CS. At this point in research, we therefore suggest evading towards choosing a single anastomotic technique for each center. Momentarily, enduring the learning curve of the surgeon has the greatest evidence in reducing postoperative complication rates.
目前的数据表明,在开放性食管切除术的线性和圆形吻合中,术后并发症可能存在差异。然而,对于越来越多的微创食管切除术(MIE),尚未对其进行总结和综述。
进行了汇总分析,包括 4 项比较 MIE 和机器人辅助微创食管切除术(RAMIE)中线性和圆形吻合技术的出版物。主要终点是吻合口漏、肺部并发症和平均住院时间。
总结了 4 项选定的出版物,在吻合口不足方面没有显示出差异(p=0.34)。术后肺部并发症也产生了类似的结果。比较圆形吻合(CS)与线性吻合(LS)并没有显示出一种有利于某种技术的趋势(p=0.82)。一些研究没有考虑学习曲线。术后吻合口狭窄没有得到足够的说明,无法对出版物进行总结。
总之,数据不足以对接受 MIE 和 RAMIE 的个别患者提供机械吻合技术的差异化建议。因此,需要进一步的 RCT 来确定 LS 和 CS 之间的潜在差异。在目前的研究中,我们建议每个中心避免选择单一的吻合技术。目前,外科医生的学习曲线对降低术后并发症发生率具有最大的证据。