长链非编码RNA H19——肝细胞癌中的新角色。
The long non-coding RNA H19 - a new player in hepatocellular carcinoma.
作者信息
Ardelt Maximilian A, Pachmayr Johanna
机构信息
Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.
Pharmacy, Pharmaceutical Biology & Clinical Pharmacy, Paracelsus Medical University, Salzburg, Austria.
出版信息
Cell Stress. 2017 Oct 1;1(1):4-6. doi: 10.15698/cst2017.10.102.
Abstract
Limited supply of nutrient normally causes cell growth arrest. Our recent study (Nat Cell Biol. (7):833-843) shows that fumarase (FH), a key enzyme responsible for the conversion between fumarate and malate in tricarboxylic acid cycle, is importantly involved in the cellular response to nutrient condition.
摘要
营养物质供应受限通常会导致细胞生长停滞。我们最近的研究（《自然细胞生物学》(7):833 - 843）表明，延胡索酸酶（FH），一种负责三羧酸循环中延胡索酸和苹果酸之间转化的关键酶，在细胞对营养状况的反应中起着重要作用。
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