Gungor Ugurlucan Funda, Yasa Cenk, Demir Omer, Dural Ozlem, Yavuz Ekrem, Akhan Suleyman Engin
Istanbul University Istanbul Faculty of Medicine, Department of Obstetrics and Gynecology, Turkey.
Istanbul University Istanbul Faculty of Medicine, Department of Pathology, Turkey.
Case Rep Obstet Gynecol. 2019 May 16;2019:1470105. doi: 10.1155/2019/1470105. eCollection 2019.
Giant vulvar condyloma is usually associated with the HPV subtypes 6 and 11 and is characterized by excessive growth of verrucous lesions on the genitals and/or perianal region. It may be observed in sexually inactive as well as sexually active women. Immunosuppression plays an important role in the development of the disease.
We report two cases of giant vulvar condyloma together with the review of the literature.
One case was a 21-year old sexually inactive woman with a history of Type 1 Diabetes. Second case was a 20-year-old sexually active woman with a rapidly progressing disease and cervical dysplasia. Both cases were operated; all the condylomatous structures were resected with preservation of the anatomy and clitoral innervation and blood flow. Skin and subcuticular dehiscence was the only complication encountered in the first case.
Main treatment of giant vulvar condyloma is surgical resection with maintenance of the vulvar anatomy. Preservation of especially the clitoral innervation as much as possible is very important.
巨大型外阴尖锐湿疣通常与人类乳头瘤病毒6型和11型相关,其特征为生殖器和/或肛周区域疣状病变过度生长。在性活跃和性不活跃的女性中均可观察到。免疫抑制在该疾病的发生发展中起重要作用。
我们报告两例巨大型外阴尖锐湿疣病例并对文献进行回顾。
一例为一名21岁性不活跃女性,有1型糖尿病病史。另一例为一名20岁性活跃女性,疾病进展迅速且有宫颈发育异常。两例均接受手术治疗;所有湿疣样结构均被切除,同时保留了解剖结构、阴蒂神经支配和血流。第一例中遇到的唯一并发症是皮肤和皮下裂开。
巨大型外阴尖锐湿疣的主要治疗方法是手术切除并维持外阴解剖结构。尽可能保留阴蒂神经支配尤为重要。