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HPV16 感染妇女外阴 Buschke-Löwenstein 肿瘤:病例报告。

Vulvar Buschke-Löwenstein tumor in a HPV 16 infected woman: case report.

机构信息

Department of Gynecology and Obstetrics, University Hospital Farhat Hached, Street Doctor Moreau, 4000 Sousse, Tunisia.

出版信息

Pan Afr Med J. 2022 May 18;42:50. doi: 10.11604/pamj.2022.42.50.35120. eCollection 2022.

DOI:10.11604/pamj.2022.42.50.35120
PMID:35949464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9338719/
Abstract

The Buschke-Löwenstein tumor is characterized by an exophytic lesion on the perianal region. It is considered benign but there is a high risk of recurrence and degenerative potential. It is commonly associated with human papillomavirus (HPV) especially subtypes 6 and 11, its evolution depends on the host's immunity and the association with other sexually transmitted diseases. Surgical excision is the recommended treatment in most cases. We report the case of a 54-year-old woman with only diabetes history, who had verrucous vulvar lesion associated to HPV subtype 16 treated with large excision.

摘要

Buschke-Löwenstein 肿瘤的特征是肛周区域有外生性病变。它被认为是良性的,但有很高的复发风险和退行性潜能。它通常与人类乳头瘤病毒(HPV)有关,特别是亚型 6 和 11,其发展取决于宿主的免疫力和与其他性传播疾病的关联。在大多数情况下,手术切除是推荐的治疗方法。我们报告了一例 54 岁女性,仅有糖尿病病史,外阴疣状病变与 HPV 亚型 16 相关,采用大切除治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc0/9338719/8d2c8fcc26d4/PAMJ-42-50-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc0/9338719/8d2c8fcc26d4/PAMJ-42-50-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdc0/9338719/8d2c8fcc26d4/PAMJ-42-50-g001.jpg

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Vulvar Buschke-Löwenstein tumor in a HPV 16 infected woman: case report.HPV16 感染妇女外阴 Buschke-Löwenstein 肿瘤:病例报告。
Pan Afr Med J. 2022 May 18;42:50. doi: 10.11604/pamj.2022.42.50.35120. eCollection 2022.
2
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本文引用的文献

1
Giant Condyloma Acuminata (Buschke-Lowenstein Tumor): Review of an Unusual Disease and Difficult to Manage.巨大尖锐湿疣( Buschke-Lowenstein 肿瘤):一种罕见且难以治疗的疾病的综述。
Infect Dis Obstet Gynecol. 2021 Jun 30;2021:9919446. doi: 10.1155/2021/9919446. eCollection 2021.
2
Position statement for the diagnosis and management of anogenital warts.肛门生殖器疣的诊断和管理立场声明。
J Eur Acad Dermatol Venereol. 2019 Jun;33(6):1006-1019. doi: 10.1111/jdv.15570. Epub 2019 Apr 10.
3
Highly aggressive Buschke-löwenstein tumor of the perineal region with fatal outcome.
侵袭性极强的会阴部Buschke-Löwenstein肿瘤,预后不良。
Indian J Dermatol Venereol Leprol. 2012 Sep-Oct;78(5):648-50. doi: 10.4103/0378-6323.100584.
4
Genital warts: a comprehensive review.尖锐湿疣:全面综述
J Clin Aesthet Dermatol. 2012 Jun;5(6):25-36.
5
Comprehensive analysis of human papillomavirus prevalence and the potential role of low-risk types in verrucous carcinoma.人乳头瘤病毒流行情况的综合分析及低危型别在疣状癌中潜在作用。
Mod Pathol. 2012 Oct;25(10):1354-63. doi: 10.1038/modpathol.2012.91. Epub 2012 Jun 8.
6
Successful treatment of buschke-löwenstein tumour by surgical excision alone.仅通过手术切除成功治疗 Buschke-Löwenstein 肿瘤。
J Cutan Aesthet Surg. 2010 Sep;3(3):174-6. doi: 10.4103/0974-2077.74496.
7
[Giant condyloma acuminata -- Buschke Lowenstein tumor (report of 3 cases)].[巨大尖锐湿疣——Buschke-Löwenstein瘤(3例报告)]
Prog Urol. 2003 Jun;13(3):513-7.
8
Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases.肛管直肠和肛周区域的巨大尖锐湿疣(Buschke-Lowenstein瘤)。42例病例分析。
Dis Colon Rectum. 1994 Sep;37(9):950-7. doi: 10.1007/BF02052606.