透明晶体立方碳化硅玻璃电极可实现电化学和光学显微镜的同步操作。

Transparent crystalline cubic SiC-on-glass electrodes enable simultaneous electrochemistry and optical microscopy.

作者信息

Phan Hoang-Phuong, Masud Mostafa Kamal, Vadivelu Raja Kumar, Dinh Toan, Nguyen Tuan-Khoa, Ngo Kieu, Dao Dzung Viet, Shiddiky Muhammad J A, Hossain Md Shahriar A, Yamauchi Yusuke, Nguyen Nam-Trung

机构信息

Queensland Micro-Nanotechnology Centre, Griffith University, Qld, Australia.

出版信息

Chem Commun (Camb). 2019 Jul 4;55(55):7978-7981. doi: 10.1039/c9cc03082d.

DOI:10.1039/c9cc03082d

PMID:31225573

Abstract

This work presents crystalline SiC-on-glass as a transparent, robust, and optically stable electrode for simultaneous electrochemical characterization and optical microscope imaging. Experimental results show a large potential window, as well as excellent stability and repeatability over multiple cyclic voltammetric scans in common redox biomarkers such as ruthenium hexaammine and methylene blue. The high optical transmittance and biocompatibility of SiC-on-glass were also observed, enabling cell culture, electrical stimulation, and high resolution fluorescence imaging. This new platform opens exciting opportunities in multi-functional biosensing-probes and observation.

摘要

这项工作展示了玻璃上的晶体碳化硅作为一种透明、坚固且光学稳定的电极，可用于同时进行电化学表征和光学显微镜成像。实验结果表明，在诸如六氨合钌和亚甲蓝等常见氧化还原生物标志物的多次循环伏安扫描中，该电极具有较大的电位窗口，以及出色的稳定性和可重复性。还观察到玻璃上碳化硅具有高光学透射率和生物相容性，能够进行细胞培养、电刺激和高分辨率荧光成像。这个新平台为多功能生物传感探针和观察带来了令人兴奋的机遇。