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气道高反应性:治疗意义。

Airway hyperresponsiveness: therapeutic implications.

作者信息

Cockcroft D W

机构信息

Department of Medicine, University Hospital, Saskatoon, Saskatchewan, Canada.

出版信息

Ann Allergy. 1987 Dec;59(6):405-14.

PMID:3122604
Abstract

In summary, this article has reviewed the importance of airway inflammation in the pathogenesis of asthma. Inflammatory triggering factors (allergen, low molecular weight sensitizing chemicals, viral URTI) are more important in the pathogenesis of asthma than the bronchospastic triggering factors. Likewise, anti-inflammatory treatment strategies (environmental control, sodium cromoglycate, steroids) are more important in the long-term control of asthma than are the purely bronchodilator strategies.

摘要

总之,本文回顾了气道炎症在哮喘发病机制中的重要性。炎症触发因素(变应原、低分子量致敏化学物质、病毒性上呼吸道感染)在哮喘发病机制中比支气管痉挛触发因素更为重要。同样,抗炎治疗策略(环境控制、色甘酸钠、类固醇)在哮喘的长期控制中比单纯的支气管扩张剂策略更为重要。

相似文献

1
Airway hyperresponsiveness: therapeutic implications.气道高反应性:治疗意义。
Ann Allergy. 1987 Dec;59(6):405-14.
2
Airway hyperresponsiveness and late asthmatic responses.气道高反应性和迟发性哮喘反应。
Chest. 1988 Jul;94(1):178-80. doi: 10.1378/chest.94.1.178.
3
New trends in asthma.哮喘的新趋势
J Med Liban. 1993;41(1):27-31.
4
[Treatment of asthma].[哮喘的治疗]
Rev Med Liege. 1973 Dec 1;28(23):822-7.
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[Bronchial asthma. Long-term therapy and prognosis].
Monatsschr Kinderheilkd. 1983 Mar;131(3):128-31.
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[Drugs for the treatment of asthma. Part II: Theophylline, disodium cromoglycate and steroids (author's transl)].
Rev Med Chil. 1980 Jun;108(6):570-6.
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Therapy of asthma in adults: the control of bronchial inflammation.
Eur Respir J Suppl. 1989 Jun;6:540s-544s.
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Management of childhood asthma.儿童哮喘的管理
J Ark Med Soc. 1980 Apr;76(11):474-7.
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Modern aspects in diagnosis and treatment of the asthmatic patient.哮喘患者诊断与治疗的现代进展。
Clin Notes Respir Dis. 1976 Fall;15(2):3-13.
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Strategies in the control of asthma.
Med Clin North Am. 1981 Sep;65(5):1033-43. doi: 10.1016/s0025-7125(16)31487-0.

引用本文的文献

1
Out-patient management of bronchial asthma.支气管哮喘的门诊管理
Can Fam Physician. 1989 Jul;35:1503-7.
2
Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae).由屋尘螨(粉尘螨)诱发的恒河猴过敏性哮喘。
Am J Pathol. 2001 Jan;158(1):333-41. doi: 10.1016/S0002-9440(10)63973-9.
3
Childhood asthma--advances in pathogenesis.
Indian J Pediatr. 1996 Jan-Feb;63(1):25-36. doi: 10.1007/BF02823862.
4
Etiology and pathogenesis of airway disease in children and adults from rural communities.农村社区儿童和成人气道疾病的病因及发病机制。
Environ Health Perspect. 1999 Jun;107 Suppl 3(Suppl 3):393-401. doi: 10.1289/ehp.99107s3393.
5
Relation between response to exercise and diurnal variability of peak expiratory flow in primary school children.小学儿童运动反应与呼气峰值流量日变化之间的关系。
Thorax. 1993 Mar;48(3):249-53. doi: 10.1136/thx.48.3.249.
6
Airway hyperresponsiveness, prevalence of chronic respiratory symptoms, and lung function in workers exposed to irritants.暴露于刺激性物质的工人的气道高反应性、慢性呼吸道症状患病率及肺功能
Occup Environ Med. 1994 Jan;51(1):3-13. doi: 10.1136/oem.51.1.3.
7
Variability of peak expiratory flow rate in children: short and long term reproducibility.儿童呼气峰值流速的变异性:短期和长期可重复性
Thorax. 1995 Jan;50(1):35-9. doi: 10.1136/thx.50.1.35.
8
Mediator and cellular mechanisms in asthma. The Philip Ellman lecture 1990.哮喘中的介质与细胞机制。菲利普·埃尔曼讲座,1990年
J R Coll Physicians Lond. 1990 Oct;24(4):304-12.
9
The protective effect of a beta 2 agonist against excessive airway narrowing in response to bronchoconstrictor stimuli in asthma and chronic obstructive lung disease.β2 激动剂对哮喘和慢性阻塞性肺疾病中支气管收缩刺激引起的气道过度狭窄的保护作用。
Thorax. 1991 Jan;46(1):9-14. doi: 10.1136/thx.46.1.9.