J Am Pharm Assoc (2003). 2019 Sep-Oct;59(5):727-735. doi: 10.1016/j.japh.2019.05.010. Epub 2019 Jun 21.
To embed pharmacy residents in an interprofessional nephrology clinic to conduct medication reconciliation in targeted high-risk patients with nondialysis kidney disease.
This pilot was a prospective quality improvement initiative conducted in an interprofessional outpatient nephrology clinic.
The nephrology clinic team includes nephrology providers, a social worker, and a geriatrician. The team is responsible for the management of conditions such as nondialysis kidney disease, resistant hypertension, acute kidney injury, proteinuria, and nephropathy.
Primary outcomes included the number and type of medication discrepancies and drug therapy problems identified. Secondary outcomes included the changes in care process directly resulting from the pharmacy residents' recommendations. The perceived value of the pharmacy residents to the interprofessional team was assessed through postintervention anonymous surveys and semistructured interviews.
The pharmacy residents conducted 118 visits for 87 unique patients (mean age 73 years, 97% male) with nondialysis kidney disease (89% stages III-V), polypharmacy (87% of patients taking > 10 medications), and a heavy comorbidity burden (85% hypertension, 80% dyslipidemia, 59% diabetes mellitus type II) from January to October 2017. Pharmacists identified 344 medication discrepancies and 301 drug therapy problems, resulting in 398 changes in care process. The most frequently identified discrepancies and drug therapy problems were the omission of an active medication from the medication list (86 of 344 discrepancies, 25%) and potentially inappropriate medications (106 of 301 drug therapy problems, 35%). Pharmacists recommended 228 medication changes, provided 76 adherence devices, facilitated 24 consults or referrals, and communicated with the primary care team on 70 occasions. The interprofessional team members all strongly agreed that patients and the team benefited from the pharmacists' involvement.
Pharmacy resident-led medication reconciliation resulted in the identification and resolution of medication discrepancies and drug therapy problems, leading to changes in the care process.
将住院药剂师纳入跨专业肾病诊所,以针对非透析肾脏疾病的高危患者进行药物治疗重整。
本研究是在跨专业门诊肾病诊所进行的前瞻性质量改进计划。
肾病诊所团队包括肾病专家、社工和老年病专家。该团队负责管理非透析肾脏疾病、难治性高血压、急性肾损伤、蛋白尿和肾病等疾病。
主要结果包括发现的药物差异和药物治疗问题的数量和类型。次要结果包括直接源于住院药剂师建议的护理过程的变化。通过干预后匿名调查和半结构化访谈评估住院药剂师对跨专业团队的价值。
住院药剂师于 2017 年 1 月至 10 月期间为 87 名非透析肾脏疾病(89%为 III-V 期)、合并用药(87%患者服用>10 种药物)和高合并症负担(85%高血压、80%血脂异常、59% II 型糖尿病)的 87 名独特患者进行了 118 次就诊。药剂师发现 344 处用药差异和 301 项药物治疗问题,导致 398 项护理过程的改变。最常发现的差异和药物治疗问题是药物清单中遗漏一种活性药物(344 处差异中有 86 处,25%)和潜在不适当药物(301 项药物治疗问题中有 106 处,35%)。药剂师建议 228 项药物更改,提供 76 个用药依从性工具,促进 24 次会诊或转诊,并与初级保健团队沟通 70 次。跨专业团队成员均强烈认为患者和团队受益于药剂师的参与。
住院药剂师主导的药物治疗重整可发现并解决药物差异和药物治疗问题,从而改变护理过程。