Koronkowski Michael J, Semla Todd P, Schmader Kenneth E, Hanlon Joseph T
Department of Pharmacy Practice, College of Pharmacy, University of Illinois, Chicago, Illinois.
Department of Veterans Affairs, Pharmacy Benefits Management Services, Hines, Illinois.
J Am Geriatr Soc. 2017 Jul;65(7):1401-1405. doi: 10.1111/jgs.14887. Epub 2017 Mar 28.
Medications can pose considerable risk in older adults. This article annotates four articles addressing this concern from 2016. The first provides national data on the use of specific prescription, over-the-counter and dietary supplements in older adults and their change over time. The second discusses the opportunity of deprescribing ineffective/unnecessary stool softeners (i.e., docusate) routinely given to older hospital patients. The third national study examines common adverse drug events in older emergency room patients. Finally, a study published demonstrating a potential association between melatonin and fractures is discussed. This manuscript is intended to provide a narrative review of key publications in medication safety for clinicians and researchers committed to improving medication safety in older adults.
药物治疗在老年人中可能带来相当大的风险。本文对2016年论述这一问题的四篇文章进行了注释。第一篇提供了关于老年人使用特定处方药、非处方药和膳食补充剂的全国性数据及其随时间的变化情况。第二篇讨论了停止给老年住院患者常规使用无效/不必要的软化大便药物(即多库酯)的机会。第三项全国性研究调查了老年急诊患者常见的药物不良事件。最后,讨论了一项已发表的研究,该研究表明褪黑素与骨折之间可能存在关联。本手稿旨在为致力于提高老年人用药安全性的临床医生和研究人员提供有关用药安全关键出版物的叙述性综述。