Thierry Adoukonou, Donald Accrombessi, Mendinatou Agbétou, Dismand Houinato
Unité d'Enseignement et de Recherche de Neurologie, Faculté de Médecine, Université de Parakou, Benin.
Service de Neurologie, CHU Parakou, Benin.
Pan Afr Med J. 2019 Feb 7;32:69. doi: 10.11604/pamj.2019.32.69.16897. eCollection 2019.
Cerebrovascular accidents (strokes) are one of the main acquired causes of epilepsy in adults, but little data are available on the incidence of epilepsy after a stroke in Africa. This study aims to estimate the impact of epilepsy in stroke patients in Parakou.
We conducted a dynamic cohort study including 203 stroke patients hospitalized in the Department of Neurology at the University Hospital of Parakou. Patients with a history of epilepsy were excluded from the follow-up. Patients were monitored over a 21-month period from 1 January 2013 to 30 September 2014. Epilepsy was defined according to the International League Against Epilepsy criteria.
Patients were aged 18-99 years, with an average age of 58.4 ± 14.2 years. The median of consultation time after symptoms was 54,3 h (+/-112,9h). Ischemic strokes accounted for 45.8%, haemorrhagic strokes 31% and indeterminate strokes 23.2%. The cumulative impact of epilepsy was 17. The incidence density rate of epilepsy was 9.8 per 100 person-years. Factors associated with the occurrence of epilepsy were the educational level, the duration of hospitalization and Barthel score.
The incidence of epilepsy is very high; hence, taking into consideration the factors associated with it during the implementation of a treatment strategy may reduce its overall load.
脑血管意外(中风)是成人后天性癫痫的主要病因之一,但非洲地区中风后癫痫发病率的数据较少。本研究旨在评估帕拉库中风患者中癫痫的影响。
我们开展了一项动态队列研究,纳入了帕拉库大学医院神经科住院的203例中风患者。有癫痫病史的患者被排除在随访之外。从2013年1月1日至2014年9月30日,对患者进行了为期21个月的监测。癫痫根据国际抗癫痫联盟的标准进行定义。
患者年龄在18 - 99岁之间,平均年龄为58.4±14.2岁。症状出现后的就诊时间中位数为54.3小时(±112.9小时)。缺血性中风占45.8%,出血性中风占31%,不明类型中风占23.2%。癫痫的累积影响为17例。癫痫的发病密度率为每100人年9.8例。与癫痫发生相关的因素有教育程度、住院时间和巴氏评分。
癫痫发病率非常高;因此,在实施治疗策略时考虑与之相关的因素可能会降低其总体负担。