贝宁北部青少年和成年人中的癫痫与偏头痛

Epilepsy and Migraine Among Adolescents and Adults in Northern Benin.

作者信息

Agbetou M, Adouwekonou R, Salanon E, Houehanou C, Kossi O, Hountohotegbe E, Adoukonou T

机构信息

Department of neurology, University of Parakou, Benin.

National school for training of technicians in public health and epidemiological surveillance, University of Parakou, Benin.

出版信息

Bull Soc Pathol Exot. 2020;113(4):209-214. doi: 10.3166/bspe-2020-0142.

DOI:10.3166/bspe-2020-0142

PMID:33826268

Abstract

To study relationship between migraine and epilepsy in adolescents and adults in northern Benin in 2018, a cross-sectional study with control group was conducted at Parakou in Benin. Cases were people with epilepsy (PWE) according to ILAE (International League Against Epilepsy) definition and followed at the Neurology Department of the Teaching Hospital of Borgou. Each case was matched to three controls (population-based controls) on age, sex and living area. Migraine was defined according to the ICHD-3 beta criteria of 2013. Conditional logistic regression models were used for associations. Thirty cases and ninety controls were included. The mean age was 32 ± 15 years for the cases and 32 ± 15 years for the controls with a sex-ratio (M/W) of 1.45. Migraine frequency in PWE was 63.33% and 17.78% in controls. After adjustment there were 8 times more migraine headaches in PWE than in controls (OR = 8.53; CI 95%: 2.6-28.0; P < 0.001).Epilepsy is associated with an increased frequency of migraine headaches.

摘要

为研究2018年贝宁北部青少年和成人偏头痛与癫痫之间的关系，在贝宁的帕拉库进行了一项设有对照组的横断面研究。病例为符合国际抗癫痫联盟（ILAE）定义的癫痫患者（PWE），并在博尔古教学医院神经科接受随访。每个病例按照年龄、性别和居住地区与三名对照（基于人群的对照）进行匹配。偏头痛根据2013年的国际头痛疾病分类第三版（ICHD-3 beta）标准进行定义。采用条件逻辑回归模型分析关联性。共纳入30例病例和90名对照。病例组的平均年龄为32±15岁，对照组为32±15岁，性别比（男/女）为1.45。癫痫患者中偏头痛的发生率为63.33%，对照组为17.78%。调整后，癫痫患者偏头痛头痛的发生率是对照组的8倍（比值比=8.53；95%置信区间：2.6-28.0；P<0.001）。癫痫与偏头痛头痛发生率增加有关。