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[应用诱发电位对重型颅脑创伤进行早期预后评估]

[Early prognostic assessment using evoked potentials in severe craniocerebral trauma].

作者信息

Riffel B, Stöhr M, Trost E, Ullrich A, Graser W

机构信息

Neurologische Klinik mit klinischer Neurophysiologie, Zentralklinikum Augsburg.

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1987 Dec;18(4):192-9.

PMID:3123196
Abstract

103 patients in acute posttraumatic coma were assessed during 72 hours following severe head injury by clinical examinations (documented with a modified Glasgow-Coma-Score and a brain-stem-score and brainstem auditory evoked potentials (BAEP) as well as short latency somatosensory evoked potentials (SEP). Patient outcomes were classified at 6 months or more, according to the following categories: good recovery, severely disabled or vegetative, and brain dead. Patients who had died by systemic complications were excluded from the study. The Glasgow-Coma-Score was reliable in forecasting a favorable outcome, but tended to produce false-pessimistic predictions. The brainstemscore and the BAEPs were reliable predictors of an unfavorable but not a favorable outcome. SEP data however, performed well as a prognostic indicant in predicting an unfavorable as well as a favorable outcome. Using the BAEP, the amplitude ratio Wave V/Wave I is more sensitive to detect a lesion than the interpeak-latency Wave I-Wave V, and--using the SEP--the amplitude ratio N20/N13b (over C2) is more sensitive than the central conduction time (N13a (over C7)--N20).

摘要

在严重颅脑损伤后的72小时内,对103例急性创伤后昏迷患者进行了评估,评估方法包括临床检查(用改良格拉斯哥昏迷评分、脑干评分记录)、脑干听觉诱发电位(BAEP)以及短潜伏期体感诱发电位(SEP)。患者结局在6个月或更长时间后根据以下类别进行分类:恢复良好、严重残疾或植物人状态以及脑死亡。因全身并发症死亡的患者被排除在研究之外。格拉斯哥昏迷评分在预测良好结局方面可靠,但往往会产生假阴性预测。脑干评分和BAEP是不良结局而非良好结局的可靠预测指标。然而,SEP数据在预测不良结局和良好结局方面作为预后指标表现良好。使用BAEP时,波幅比V波/I波比峰间潜伏期I波-V波更能敏感地检测病变;使用SEP时,波幅比N20/N13b(C2电极处)比中枢传导时间(C7电极处N13a-N20)更敏感。

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