Ahmadi Ali, Sodejani Soghra Ahmadi, Malekzadeh Reza, Poustchi Hossein, Solati Kamal
Modeling in Health Research Center and School of Public Health, Department of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Diabetes Metab Syndr. 2019 May-Jun;13(3):2170-2174. doi: 10.1016/j.dsx.2019.05.006. Epub 2019 May 17.
Stress is one of the most common and controllable risk factors for non-communicable diseases. The purpose of this study was to determine the relationship between stress and biochemical factors and hematologic indices.
The data to conduct this cross-sectional study were obtained from Shahrekord Cohort Study (SCS). The sample size included 1000 people who were randomly selected from 7000 people enrolled in the SCS conducted in 2017-2018. To measure stress as well as blood biochemical factors and hematologic indices, the Questionnaire of Stressful Life Events and Glucose and Lipid profile were used, respectively.
Among stress dimensions, job security was significantly associated with most biochemical factors and hematologic indices. Linear regression model showed that there was a significant correlation between stress and blood urea, liver enzymes (ALT and AST), education, marital status, and occupation.
This study reported that the level of exposure to stressors was higher than that of other studies, and the results of this study are recommended to be used for screening and early detection of the consequences of exposure to chronic stressors, especially for the prevention of cardiovascular diseases.
压力是非传染性疾病最常见且可控的风险因素之一。本研究旨在确定压力与生化因素及血液学指标之间的关系。
开展这项横断面研究的数据取自设拉子队列研究（SCS）。样本量包括从2017 - 2018年进行的SCS所纳入的7000人中随机选取的1000人。分别使用应激生活事件问卷和血糖与血脂谱来测量压力以及血液生化因素和血液学指标。
在压力维度中，工作保障与大多数生化因素和血液学指标显著相关。线性回归模型显示，压力与血尿素、肝酶（谷丙转氨酶和谷草转氨酶）、教育程度、婚姻状况及职业之间存在显著相关性。
本研究报告称，应激源的暴露水平高于其他研究，建议将本研究结果用于筛查和早期发现慢性应激源暴露的后果，尤其是用于预防心血管疾病。
