Nakada Taka-Aki, Oda Shigeto, Abe Ryuzo, Hattori Noriyuki
Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo, Chiba, 260-8677, Japan.
J Artif Organs. 2020 Mar;23(1):14-18. doi: 10.1007/s10047-019-01113-7. Epub 2019 Jun 24.
Acute blood purification therapy is an essential artificial organ in critical care. In the review article, looking back on the history, we describe our present knowledge and techniques of acute blood purification therapy in critical care. The topics include continuous hemodiafiltration (CHDF), online HDF as an artificial liver support, blood purification therapy aiming to remove pathogenic substances of sepsis, a procedure for connecting a CRRT device into an extra-corporeal membrane oxygenation circuit, and replacement fluid for CHDF. We also raise remaining issues and clarify the future direction of acute blood purification therapy in critical care. This review was created based on a translation of the Japanese review written in the Japanese Journal of Artificial Organs in 2017 (Vol. 46, No. 1, pp. 67-70), with adding some references.
急性血液净化疗法是重症监护中的重要人工器官。在这篇综述文章中，我们回顾历史，阐述了目前重症监护中急性血液净化疗法的知识和技术。主题包括连续性血液透析滤过（CHDF）、作为人工肝支持的在线血液透析滤过、旨在清除脓毒症致病物质的血液净化疗法、将连续性肾脏替代治疗（CRRT）设备连接到体外膜肺氧合回路的操作以及CHDF的置换液。我们还提出了尚存的问题，并阐明了重症监护中急性血液净化疗法的未来方向。这篇综述是基于对2017年发表于《日本人工器官杂志》（第46卷，第1期，第67 - 70页）的日文综述的翻译，并补充了一些参考文献而撰写的。
