特发性颅内高压的伴用扫频源光相干断层扫描的神经纤维层筛板表面位置。
Lamina cribrosa surface position in idiopathic intracranial hypertension with swept-source optical coherence tomography.
机构信息
Department of Neuro-Ophthalmology, Beyoglu Eye Training and Research Hospital, Istanbul, Turkey.
出版信息
Indian J Ophthalmol. 2019 Jul;67(7):1085-1088. doi: 10.4103/ijo.IJO_1736_18.
PURPOSE
The purpose of this study is to compare the thickness and depth measurements of the lamina cribrosa (LC) obtained using a swept-source optical coherence tomography (SS-OCT) device in idiopathic intracranial hypertension (IIH) patients and healthy subjects.
METHODS
This retrospective, cross-sectional observational study included 16 eyes with IIH and 20 control eyes. The LC measurements with serial horizontal B scans of the optic nerve head were obtained using SS-OCT (Topcon 3D DRI OCT Triton). The anterior lamina surface (ALS) depth, posterior lamina surface (PLS) depth, and LC thickness measurements were evaluated.
RESULTS
In patients with IIH, the mean ALS depth was 225.00 ± 58.57 μm and the mean PLS depth was 449.75 ± 63.50 μm. In the IIH control group, the corresponding values were 359.40 ± 105.38 and 570.10 ± 99.41 μm (P < 0.05). The difference in LC thickness between the IIH and control subjects was not statistically significant.
CONCLUSION
LC can be evaluated using an SS-OCT device. LC was displaced anteriorly in patients with IIH compared with normal controls. The assessment of LC level with SS-OCT in IIH cases is a valuable and reproducible adjunctive imaging method in terms of diagnosis and follow-up.
目的
本研究旨在比较特发性颅内高压（IIH）患者和健康受试者使用扫频源光学相干断层扫描（SS-OCT）设备获得的颅神经筛板（LC）的厚度和深度测量值。
方法
本回顾性、横断面观察性研究纳入了 16 只 IIH 眼和 20 只对照眼。使用 SS-OCT（Topcon 3D DRI OCT Triton）对视神经头的连续水平 B 扫描进行 LC 测量。评估前 LC 表面（ALS）深度、后 LC 表面（PLS）深度和 LC 厚度测量值。
结果
在 IIH 患者中，平均 ALS 深度为 225.00 ± 58.57 μm，平均 PLS 深度为 449.75 ± 63.50 μm。在 IIH 对照组中，相应值分别为 359.40 ± 105.38 μm 和 570.10 ± 99.41 μm（P < 0.05）。IIH 组和对照组之间 LC 厚度的差异无统计学意义。
结论
可以使用 SS-OCT 设备评估 LC。与正常对照组相比，IIH 患者的 LC 向前移位。在 IIH 病例中，使用 SS-OCT 评估 LC 水平是一种有价值且可重复的辅助成像方法，可用于诊断和随访。
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